ArticleAmerican journal of perinatology2013
Environmental risk factors and perinatal outcomes in preterm newborns, according to family recurrence of prematurity.
Article in American journal of perinatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Environmental and genetic risk factors for preterm birth: interplays with stressful events during pregnancy.Pediatric research · 2025Article
- Genetic susceptibility for retinopathy of prematurity and its associated comorbidities.Pediatric research · 2024Article
- Gene-environment interactions and preterm birth predictors: A Bayesian network approach.Genetics and molecular biology · 2024Article
- Genes, exposures, and interactions on preterm birth risk: an exploratory study in an Argentine population.Journal of community genetics · 2022Article
- Preterm birth etiological pathways: a Bayesian networks and mediation analysis approach.Pediatric research · 2022Article
- Preterm birth and genitourinary tract infections: assessing gene-environment interaction.Pediatric research · 2021Article
- Association of candidate gene polymorphisms with clinical subtypes of preterm birth in a Latin American population.Pediatric research · 2017Article
- Maternal and neonatal epidemiological features in clinical subtypes of preterm birth.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2016Observational
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveWe analyzed the role of environmental risk factors, sociodemographic characteristics, clinical characteristics, and reproductive history in preterm births and their associated perinatal outcomes in families classified according to their histories of preterm recurrence among siblings. STUDY
designA retrospective study was conducted at Nuestra Señora de la Merced Maternity Hospital in the city of Tucumán, Argentina. A total of 348 preterm, non-malformed, singleton children born to multipara women were reviewed. The family history score described by Khoury was applied, and families were classified as having no, medium, or high genetic aggregation.
resultsFamilies with no familial aggregation showed a higher rate of short length of cohabitation, maternal urinary tract infections during the current pregnancy, and maternal history of miscarriage during the previous pregnancy. Families with a high level of aggregation had a significantly higher incidence of pregnancy complications, such as diabetes, hypertension, and immunologic disorders.
conclusionReproductive histories clearly differed between the groups, suggesting both a different response to environmental challenges based on genetic susceptibility and the activation of different pathophysiological pathways to determine the duration of pregnancy in each woman.
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