Evidence map›Paper›PMID 23131820›Full record

ArticleThe journal of nutrition, health & aging2012

Physical function mitigates the adverse effects of being thin on mortality in a free-living older Taiwanese cohort.

M-S Lee, R C-Y Chen, Y-H Chang, Y-C Huang, M L Wahlqvist

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Article in The journal of nutrition, health & aging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

M-S LeeSchool of Public Health, National Defense Medical Center, 161 Minchuan East Road, Sec. 6, Taipei 114, Taiwan, ROC. profmlw@nhri.org.tw
R C-Y Chen
Y-H Chang
Y-C Huang
M L Wahlqvist

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo examine the significance of underweight and physical function as well as their interaction on mortality in the aged.

designProspective cohort.

settingThe Elderly Nutrition and Health Survey in Taiwan during 1999-2000.

participantsTotal of 1435 representative free-living elders (739 men and 696 women). MEASUREMENTS: Body composition was assessed by various anthropometrics. Physical function score (PF, ranged 0-100) was derived from the SF-36(®). Death by December 31, 2006 was the outcome measure.

resultsAfter 7.9 (median: 7.0) years follow-up, 381 (223 men, 158 women) of 1435 eligible participants had died. Those with the lowest PF (<45) had 3.43 (hazards ratio (HR), 95% confidence interval (CI) = 2.20-5.36) times the all-cause mortality risk of the highest PF (≥58). Interactions for PF and BMI (P =0.02) and for PF and wrist circumference (P =0.09) on death were found after controlling for potential confounders. Jointly, compared to normal-BMI-highest-PF, the greatest HR for death occurred where BMI <18.5 kg/m2 was combined with the lowest-PF after covariate adjustments (HR = 8.67, 95% CI = 3.77-20.0). Similarly, the lowest arm muscle circumference (MAMC)-PF had a HR of 5.22 compared to mid-MAMC-highest-PF. However, percent and absolute body fat, estimated by bioelectrical impedance, was comparable to non-sarcopenic individuals.

conclusionThin elderly Taiwanese with sarcopenia, and less skeleton, are at the most risk of death, especially if physical function is limited.

Indexed as

Body CompositionBody Mass IndexCause of DeathGeriatric AssessmentPhysical FitnessAdipose TissueAgedAged, 80 and overArmBone and BonesConfidence IntervalsFemaleHealth SurveysHumansMaleMuscle, Skeletal

Identifiers

PMID23131820
PMCPMC12878527

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.