ArticleThe journal of nutrition, health & aging2012
The protective effect of calcium on bone mass in postmenopausal women with high selenium intake.
Article in The journal of nutrition, health & aging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Dietary Copper Intake and Bone Health: A Systematic Review and Meta-Analysis of Observational Studies.Calcified tissue international · 2025Pooled it
- The Role of Copper Intake in Bone Health: A Quantitative Analysis in Postmenopausal Spanish Women.European journal of investigation in health, psychology and education · 2025Article
- Reactive sulfur and selenium species in the regulation of bone homeostasis.Free radical biology & medicine · 2022Review
- The Role of Selenium in Pathologies: An Updated Review.Antioxidants (Basel, Switzerland) · 2022Review
- The Effects of Selenium on Bone Health: From Element to Therapeutics.Molecules (Basel, Switzerland) · 2022Review
- Dietary consumption of selenium inversely associated with osteoporosis in postmenopausal women.Frontiers in nutrition · 2022Article
- Article
- Do Only Calcium and Vitamin D Matter? Micronutrients in the Diet of Inflammatory Bowel Diseases Patients and the Risk of Osteoporosis.Nutrients · 2021Review
- Relationship between Selected Trace Elements in Human Milk and Psychosocial Characteristics in Korean Early Postpartum Women.International journal of environmental research and public health · 2021Article
- Article
- Association between dietary selenium intake and the prevalence of osteoporosis: a cross-sectional study.BMC musculoskeletal disorders · 2019Article
- Evaluation of the Dietary Intake of Cadmium, Lead and Mercury and Its Relationship with Bone Health among Postmenopausal Women in Spain.International journal of environmental research and public health · 2017Article
- Lean Mass Appears to Be More Strongly Associated with Bone Health than Fat Mass in Urban Black South African Women.The journal of nutrition, health & aging · 2015Article
- Diet, weight, cytokines and bone health in postmenopausal women.The journal of nutrition, health & aging · 2014Article
- Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveNutritional factors, especially the two essential nutrients calcium and vitamin D, have been shown to play an important role in bone health. We wanted to determine the possible protective effect of calcium intake in adequate amounts on bone mass as assessed by quantitative ultrasound in postmenopausal women who also have a high intake of selenium.
settingHealth district of Cáceres, Spain. PARTICIPANTS AND STUDY
design335 postmenopausal women aged 60.9 (SD = 8.1) years. Women were stratified based on the vitamin D, vitamin E, calcium intake and the calcium/protein and calcium/phosphorous index. MEASUREMENTS: Bone status (Ad-SoS measured at the phalanges) was assessed with an ultrasound device model DBM Sonic 1200R. Food intake was quantified using dietetic scales, measuring cups, and spoons based on 7 days of diet records. Urine samples were collected the morning of testing after an overnight fast. Venous blood samples for the hematological and biochemical studies were also obtained in the fasting state.
resultsIn the group of women with Ca intake < 800 mg / d we found a significant and negative relationship between Ad-SoS with age (β= -4.020, F = 23.327) and selenium intake (β = -0.419, F = 10.067), as well as a positive relationship with Ca intake (β= 0.104 and F = 7.084) (p <0.0001 in all). In the group of women with Ca intake > 800 mg / d, age has a significant and negative relationship (β = -4.829 and F = 106.745), whereas folic acid intake has a significant and positive relationship (β = 0.047 and F = 5.858) (p <0.0001 in both).
conclusionElevated selenium intake negatively affects bone mass measurements in postmenopausal women over the age of 51 but only if calcium intake is also less than 800 mg / day. When calcium intake is greater than 800 mg/day, selenium did not appear to affect bone mass.
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