ArticleCerebral cortex (New York, N.Y. : 1991)2014
Radial coherence of diffusion tractography in the cerebral white matter of the human fetus: neuroanatomic insights.
Article in Cerebral cortex (New York, N.Y. : 1991), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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57 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Novel imaging techniques to study postmortem human fetal anatomy: a systematic review on microfocus-CT and ultra-high-field MRI.European radiology · 2020Pooled it
- Insights into temporal and spatial dynamics of short association fiber formation in the human fetal brain.Science advances · 2026Article
- Developmental human brain connectome from fetal stage to early childhood.Developmental cognitive neuroscience · 2026Review
- Structural pathways related to the subventricular zone are decreased in volume with altered microstructure in young adult males with autism spectrum disorder.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Regional Changes in the Fetal Telencephalic Wall Diffusion Metrics Across Late Second and Third Trimesters.Human brain mapping · 2025Article
- White Matter Tract Crossing and Bottleneck Regions in the Fetal Brain.Human brain mapping · 2025Article
- Ex vivo Magnetic Resonance Imaging of the Human Fetal Brain.Developmental neuroscience · 2025Review
- Streamline tractography of the fetal brain in utero with machine learning.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Prenatal assessment of brain malformations on neuroimaging: an expert panel review.Brain : a journal of neurology · 2024Review
- Article
- Anatomically constrained tractography of the fetal brain.NeuroImage · 2024Article
- Advances in Fetal Brain Imaging.Magnetic resonance imaging clinics of North America · 2024Review
- Dynamic changes in subplate and cortical plate microstructure at the onset of cortical folding in vivo.bioRxiv : the preprint server for biology · 2024Article
- Characterizing microstructural development in the fetal brain using diffusion MRI from 23 to 36 weeks of gestation.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Article
- Detailed anatomic segmentations of a fetal brain diffusion tensor imaging atlas between 23 and 30 weeks of gestation.Human brain mapping · 2023Article
- Mapping Human Brain Pathways: Challenges and Opportunities in the Integration of Scales.Brain, behavior and evolution · 2023Review
- A comparative study of the superior longitudinal fasciculus subdivisions between neonates and young adults.Brain structure & function · 2022Article
- microRNA Biology on Brain Development and Neuroimaging Approach.Brain sciences · 2022Review
- Identification of association fibers using ex vivo diffusion tractography in Alexander disease brains.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
High angular resolution diffusion imaging (HARDI) demonstrates transient radial coherence of telencephalic white matter in the human fetus. Our objective was to define the neuroanatomic basis of this radial coherence through correlative HARDI- and postmortem tissue analyses. Applying immunomarkers to radial glial fibers (RGFs), axons, and blood vessels in 18 cases (19 gestational weeks to 3 postnatal years), we compared their developmental profiles to HARDI tractography in brains of comparable ages (n = 11). At midgestation, radial coherence corresponded with the presence of RGFs. At 30-31 weeks, the transition from HARDI-defined radial coherence to corticocortical coherence began simultaneously with the transformation of RGFs to astrocytes. By term, both radial coherence and RGFs had disappeared. White matter axons were radial, tangential, and oblique over the second half of gestation, whereas penetrating blood vessels were consistently radial. Thus, radial coherence in the fetal white matter likely reflects a composite of RGFs, penetrating blood vessels, and radial axons of which its transient expression most closely matches that of RGFs. This study provides baseline information for interpreting radial coherence in tractography studies of the preterm brain in the assessment of the encephalopathy of prematurity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.