Evidence map›Paper›PMID 23131601›Full record

ArticleJournal of the International Neuropsychological Society : JINS2011

Explaining differences in episodic memory performance among older African Americans and Whites: the roles of factors related to cognitive reserve and test bias.

Denise C Fyffe, Shubhabrata Mukherjee, Lisa L Barnes, Jennifer J Manly, David A Bennett, Paul K Crane

Abstract readComparative Study
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Measurement bias for age, sex, and years of education in selected RDoC tasks.Journal of clinical and experimental neuropsychology · 2026
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  5. Cognitive screening biases in a secondary prevention Alzheimer's disease clinical trial.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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  12. Examining cross-sectional and longitudinal relationships between multidomain physical fitness metrics, education, and cognition in Black older adults.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2024
    Article
  13. Article
  14. Cross-cultural Diagnostic Validity of the Multilingual Naming Test (MINT) in a Sample of Older Adults.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024
    Article
  15. Review
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  17. Review
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  19. Intersectionality in Alzheimer's Disease: The Role of Female Sex and Black American Race in the Development and Prevalence of Alzheimer's Disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Denise C FyffeSpinal Cord Injury/Outcomes & Assessment Research Laboratory, Kessler Foundation Research Center, West Orange, NJ 07052, USA. dfyffe@kesslerfoundation.org
Shubhabrata Mukherjee
Lisa L Barnes
Jennifer J Manly
David A Bennett
Paul K Crane

Funding

EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
Risk Factors for Cognitive Decline in African-AmericansR01AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2004 to 2025
$18.2M
Improving Cognitive Outcome Precision & Responsiveness with Modern PsychometricsR01AG029672 · NIA · UNIVERSITY OF WASHINGTON · PI CRANE, PAUL K · 2007 to 2021
$7.0M
Conference on Advanced Psychometric Methods in Cognitive Aging ResearchR13AG030995 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MUNGAS, DAN M. · 2008 to 2022
$620k
NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG022018NIA NIH HHS R01AG022018NIA NIH HHS R01 AG029672NIA NIH HHS R01AG029672NIA NIH HHS R01AG17917NIA NIH HHS R13 AG030995
6 · The paper itself

Abstract

Older African Americans tend to perform poorly in comparison with older Whites on episodic memory tests. Observed group differences may reflect some combination of biological differences, measurement bias, and other confounding factors that differ across groups. Cognitive reserve refers to the hypothesis that factors, such as years of education, cognitive activity, and socioeconomic status, promote brain resilience in the face of pathological threats to brain integrity in late life. Educational quality, measured by reading test performance, has been postulated as an important aspect of cognitive reserve. Previous studies have not concurrently evaluated test bias and other explanations for observed differences between older African Americans and Whites. We combined data from two studies to address this question. We analyzed data from 273 African American and 720 White older adults. We assessed DIF using an item response theory/ordinal logistic regression approach. DIF and factors associated with cognitive reserve did not explain the relationship between race, and age- and sex-adjusted episodic memory test performance. However, reading level did explain this relationship. The results reinforce the importance of considering education quality, as measured by reading level, when assessing cognition among diverse older adults.

Indexed as

Memory, EpisodicAgedAged, 80 and overBiasBlack or African AmericanCognitive ReserveData Interpretation, StatisticalDemographyEducational StatusFemaleHumansMaleNeuropsychological TestsPsychomotor PerformanceReadingRegression Analysis

Identifiers

PMID23131601
PMCPMC3496282

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.