Evidence map›Paper›PMID 23130754›Full record

Trial reportBMC family practice2012

Opportunistic detection of atrial fibrillation in subjects aged 65 years or older in primare care: a randomised clinical trial of efficacy. DOFA-AP study protocol.

Luis Á Pérula-de-Torres, Miguel Á Martínez-Adell, Virginia González-Blanco, José M Baena-Díez, Enrique Martín-Rioboó, Juan M Parras-Rejano, Jesús González-Lama, Remedios Martín-Alvarez, Roger Ruiz-Moral, José Á Fernández-García and 11 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC family practice, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01291953 (Effectiveness of Early Detection of Atrial Fibrillation in People 65 Years or More bt Physicians and Nurse in Primary Care), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01291953 nacompletednot on this map

Effectiveness of Early Detection of Atrial Fibrillation in People 65 Years or More bt Physicians and Nurse in Primary Care

TypeinterventionalSponsorHospital Universitario Reina Sofia de CordobaRan2011 to 2015Enrolled6,990ConditionsAtrial FibrillationArmsScreening, Control
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 1 country.

Luis Á Pérula-de-TorresUnidad Docente de Medicina Familiar y Comunitaria de Córdoba, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)/Hospital Universitario Reina Sofía/Universidad de Córdoba, Avda, Menéndez Pidal, s/n, Córdoba, 14004, Spain. luisangel.perula@gmail.com
Miguel Á Martínez-Adell
Virginia González-Blanco
José M Baena-Díez
Enrique Martín-Rioboó
Juan M Parras-Rejano
Jesús González-Lama
Remedios Martín-Alvarez
Roger Ruiz-Moral
José Á Fernández-García
Modesto Pérez-Díaz
Joaquin Ruiz-de-Castroviejo
Carlos Pérula-de-Torres
Antonio Valero-Martín
Ana Roldán-Villalobos
Margarita Criado-Larumbe
Emili Burdoy-Joaquín
Montserrat Coma-Solé
Mercè Cervera-León
Lluís Cuixart-Costa
Collaborative Group DOFA-AP
Instituto Maimónides de Investigación Biomédica de Córdoba · ESAndalusian Health Service · ESConsorci d’Atenció Primària de Salut Barcelona Esquerra · ESInstitut Català de la Salut · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical Practice Guidelines recommend using peripheral blood pulse measuring as a screening test for Atrial Fibrillation. However, there is no adequate evidence supporting the efficacy of such procedure in primary care clinical practice. This paper describes a study protocol designed to verify whether early opportunistic screening for Atrial Fibrillation by measuring blood pulse is more effective than regular practice in subjects aged 65 years attending primary care centers. METHODS/

designAn cluster-randomized controlled trial conducted in Primary Care Centers of the Spanish National Health Service. A total of 269 physicians and nurses will be allocated to one of the two arms of the trial by stratified randomization with a 3:2 ratio (three practitioners will be assigned to the Control Group for every two practitioners assigned to the Experimental Group). As many as 12 870 patients aged 65 years or older and meeting eligibility criteria will be recruited (8 580 will be allocated to the Experimental Group and 4 290 to the Control Group). Randomization and allocation to trial groups will be carried out by a central computer system. The Experimental Group practitioners will conduct an opportunistic case finding for patients with Atrial Fibrillation, while the Control Group practitioners will follow the regular guidelines. The first step will be finding new Atrial Fibrillation cases. A descriptive inferential analysis will be performed (bivariate and multivariate by multilevel logistic regression analysis). DISCUSSION: If our hypothesis is confirmed, we expect Primary Care professionals to take a more proactive approach and adopt a new protocol when a patient meeting the established screening criteria is identified. Finally, we expect this measure to be incorporated into Clinical Practice Guidelines.

trial registrationThe study is registered as NCT01291953 (ClinicalTrials.gob).

Indexed as

AgedAtrial FibrillationHumansLogistic ModelsMass ScreeningMultivariate AnalysisPrimary Health CarePulseSecondary PreventionSpain

Identifiers

PMID23130754
PMCPMC3573963
OpenAlexW2147708578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.