Evidence map›Paper›PMID 23130609›Full record

ArticleActa veterinaria Scandinavica2012

Antibody response in vaccinated pregnant mares to recent G3BP[12] and G14P[12] equine rotaviruses.

Manabu Nemoto, Hiroshi Tsunemitsu, Harutaka Murase, Yasuo Nambo, Shinsuke Sato, Yasuhiro Orita, Hiroshi Imagawa, Hiroshi Bannai, Koji Tsujimura, Takashi Yamanaka and 2 more

Open access · goldAbstract read
In one paragraph

Article in Acta veterinaria Scandinavica, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Equine rotavirus infection.Journal of equine science · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Manabu NemotoEpizootic Research Center, Equine Research Institute, Japan Racing Association, 1400-4 Shiba, Shimotsuke, Tochigi 329-0412, Japan. nemoto_manabu@epizoo.equinst.go.jp
Hiroshi Tsunemitsu
Harutaka Murase
Yasuo Nambo
Shinsuke Sato
Yasuhiro Orita
Hiroshi Imagawa
Hiroshi Bannai
Koji Tsujimura
Takashi Yamanaka
Tomio Matsumura
Takashi Kondo
Japan Racing Association · JPHidaka Hospital · JPNational Institute of Animal Health · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBoth the G3P[12] and the G14P[12] type of equine group A rotavirus (RVA) have recently become predominant in many countries, including Japan. G3 types are classified further into G3A and G3B. The G3A viruses have been circulating in Europe, Australia, and Argentina, and the G3B viruses have been circulating in Japan. However, only an inactivated vaccine containing a single G3BP[12] strain is commercially available in Japan. To assess the efficacy of the current vaccine against recently circulating equine RVA strains, we examined antibody responses in pregnant mares to recent G3BP[12] and G14P[12] strains by virus neutralization test.

findingsAfter vaccination in five pregnant mares, the geometric mean serum titers of virus-neutralizing antibody to recent G3BP[12] strains increased 5.3- to 7.0-fold and were similar to that against homologous vaccine strain. Moreover, antibody titers to recent G14P[12] strains were also increased 3.0- to 3.5-fold.

conclusionsThese results suggest that inoculation of mares with the current vaccine should provide foals with virus-neutralizing antibodies against not only the G3BP[12] but also the G14P[12] RVA strain via the colostrum.

Indexed as

AnimalsAntibodies, ViralFemaleHorse DiseasesHorsesMolecular Sequence DataNeutralization TestsPhylogenyPolymerase Chain ReactionPregnancyRotavirusRotavirus InfectionsRotavirus VaccinesSequence Analysis, DNAVaccines, InactivatedAntibodies, ViralRotavirus VaccinesVaccines, Inactivated

Identifiers

PMID23130609
PMCPMC3523035
OpenAlexW2122301539

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.