Evidence map›Paper›PMID 23130099›Full record

ArticlePulmonary circulation2012

Platelets in pulmonary vascular physiology and pathology.

Michael H Kroll, Vahid Afshar-Kharghan

Open access · bronzeAbstract read
In one paragraph

Article in Pulmonary circulation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.7field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Post-Transcriptional Expression Control in Platelet Biogenesis and Function.International journal of molecular sciences · 2020
    Review
  14. Diabetic lung disease: fact or fiction?Reviews in endocrine & metabolic disorders · 2019
    Review
  15. Article
  16. Lung as a Niche for Hematopoietic Progenitors.Stem cell reviews and reports · 2017
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Michael H KrollM.D. Anderson Cancer Center, Houston, Texas, USA.
Vahid Afshar-Kharghan
Pulmonary Associates · USThe University of Texas MD Anderson Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Almost a trillion platelets pass through the pulmonary circulation every minute, yet little is known about how they support pulmonary physiology or contribute to the pathogenesis of lung diseases. When considering this conundrum, three questions jump out: Does platelet production in the lungs occur? Why does severe thrombocytopenia-which undercuts the principal physiological role of platelets to effect hemostasis-not lead to pulmonary hemorrhage? Why does atherothrombosis-which platelets initiate, maintain, and trigger is other critically important arterial beds-not develop in the pulmonary artery? The purpose of this review is to explore these and derivative questions by providing data within a conceptual framework that begins to organize a subject that is largely unassembled.

Indexed as

cell signalinghemostasisplateletsthrombosisvascular biology

Identifiers

PMID23130099
PMCPMC3487299
OpenAlexW2091980701

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.