ArticleJournal of parasitic diseases : official organ of the Indian Society for Parasitology2009
Anthelmintic efficacy of ethanolic shoot extract of Alpinia nigra on tegumental enzymes of Fasciolopsis buski, a giant intestinal parasite.
Article in Journal of parasitic diseases : official organ of the Indian Society for Parasitology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 41 citations in OpenAlex.
- Alpikwangsides A-C, three previously undescribed compounds isolated from the rhizomes of Alpinia kwangsiensis and their NO inhibitory activity.Journal of natural medicines · 2026Article
- Evaluation of in vitro anthelmintic activity of crude extract and synthesized green silver nanoparticles of the leaves ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024Article
- Biosynthesis, characterization and anthelmintic activity of silver nanoparticles of Clerodendrum infortunatum isolate.Scientific reports · 2023Article
- In vitro study of the antioxidant, antiproliferative, and anthelmintic properties of some medicinal plants of Kokrajhar district, India.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021Article
- An overview of the chemical composition and biological activities of essential oils fromRSC advances · 2021Review
- Persicaria strigosa (R.Br.) Nakai: a natural anthelmintic?Parasitology research · 2021Article
- Phytochemical, analgesic, antibacterial, and cytotoxic effects of Alpinia nigra (Gaertn.) Burtt leaf extract.Journal of traditional and complementary medicine · 2015Article
- Alpinia: the gold mine of future therapeutics.3 Biotech · 2013Article
- Anthelmintic effect of a methanol extract of Bombax malabaricum leaves on Paramphistomum explanatum.Parasitology research · 2012Article
- Anthelmintic effect of a methanol extract of leaves of Dregea volubilis on Paramphistomum explanatum.Parasitology research · 2012Article
- Potentilla fulgens (Family Rosaceae), a medicinal plant of north-east India: a natural anthelmintic?Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2010Article
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2 authors at 1 institution in 1 country.
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Abstract
Ethanolic shoot extract of Alpinia nigra, a traditionally used anthelmintic medicinal plant among the Tripuri tribes of north-east India, was tested in vitro to determine its anthelmintic efficacy in gastrointestinal trematode Fasciolopsis buski, using alterations in the activity of vital tegumental enzymes viz. acid phosphatase (AcPase), alkaline phosphatase (AlkPase) and adenosine triphosphatase (ATPase). Live adult F. buski treated in vitro with different concentrations of the plant extract showed significant decline in the visible stain histochemically and enzyme activities. Quantitatively, the total enzyme activity of AcPase, AlkPase and ATPase was found to be reduced by 45, 41 and 43%, respectively compared to the control. The reference drug, praziquantel also showed more or less similar effect like that of the plant extract. The results suggest that the tegumental enzymes of the parasite may be an important target of action for active component(s) of A. nigra, which appears to act transtegumentally.
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