ArticleThe Journal of infectious diseases2013
Transmission of hepatitis C virus among people who inject drugs: viral stability and association with drug preparation equipment.
Article in The Journal of infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 68 citations in OpenAlex.
- Methadone and buprenorphine-naloxone are effective in reducing illicit buprenorphine and other opioid use, and reducing HIV risk behavior--outcomes of a randomized trial.Drug and alcohol dependence · 2013Trial
- Informing the Equitable Implementation of Hepatitis C Interventions: Cost-Effectiveness Modeling in Rural Populations of People Who Inject Drugs.PharmacoEconomics · 2026Article
- Finding the Context of High-Risk Behavioral Factors and the Effectiveness of Addiction Treatment Centers in Preventing the Transmission of Hepatitis C Virus Among Injecting Drug Addicts: "Southeastern Iran".Health science reports · 2025Article
- Contemporary Insights into Hepatitis C Virus: A Comprehensive Review.Microorganisms · 2024Review
- Prevalence and associated risk factors of hepatitis C antibody and RNA among people who inject drugs in Puerto Rico.Journal of substance use and addiction treatment · 2024Article
- Analysis of Patients' Characteristics and Treatment Profile of People Who Use Drugs (PWUDs) with and without a Co-Diagnosis of Viral Hepatitis C: A Real-World Retrospective Italian Analysis.Therapeutics and clinical risk management · 2023Article
- Review
- Natural Host-Environmental Media-Human: A New Potential Pathway of COVID-19 Outbreak.Engineering (Beijing, China) · 2020Article
- Harm Reduction Services to Prevent and Treat Infectious Diseases in People Who Use Drugs.Infectious disease clinics of North America · 2020Review
- Baseline prevalence and correlates of HIV and HCV infection among people who inject drugs accessing a syringe services program; Miami, FL.Harm reduction journal · 2020Article
- Navigating environmental constraints to injection preparation: the use of saliva and other alternatives to sterile water among unstably housed PWID in London.Harm reduction journal · 2020Article
- Characterization of HCV-infected people who inject drugs (PWID) in the setting of clinical care in Canada (CAPICA): A retrospective study.Canadian liver journal · 2020Article
- Differences among hepatitis C patients seen in community and specialist outpatient care settings.Canadian liver journal · 2020Article
- Opioid epidemic and liver disease.JHEP reports : innovation in hepatology · 2019Review
- Development, validation, and potential applications of the hepatitis C virus injection-risk knowledge scale (HCV-IRKS) among young opioid users in New York City.Drug and alcohol dependence · 2019Article
- "Money Helps": People who inject drugs and their perceptions of financial compensation and its ethical implications.Ethics & behavior · 2019Article
- Modeling of patient virus titers suggests that availability of a vaccine could reduce hepatitis C virus transmission among injecting drug users.Science translational medicine · 2018Article
- Recovery of Infectious Hepatitis C Virus From Injection Paraphernalia: Implications for Prevention Programs Serving People Who Inject Drugs.The Journal of infectious diseases · 2018Article
- Childhood exposures to discarded needles and other objects potentially contaminated with blood-borne pathogens in Toronto, Canada.Paediatrics & child health · 2017Article
- Social Determinants of HIV/HCV Co-Infection: A case Study from People Who Inject Drugs in Rural Puerto Rico.Addictive behaviors reports · 2017Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundHepatitis C virus (HCV) transmission among people who inject drugs remains a challenging public health problem. We investigated the risk of HCV transmission by analyzing the direct association of HCV with filters, water to dilute drugs, and water containers.
methodsExperiments were designed to replicate practices by people who inject drugs and include routinely used injection equipment. HCV stability in water was assessed by inoculation of bottled water with HCV. Viral association with containers was investigated by filling the containers with water, inoculating the water with HCV, emptying the water, and refilling the container with fresh water. Transmission risk associated with drug preparation filters was determined after drawing virus through a filter and incubating the filter to release infectious particles.
resultsHCV can survive for up to 3 weeks in bottled water. Water containers present a risk for HCV transmission, as infectious virions remained associated with water containers after washing. Physical properties of the water containers determined the degree of HCV contamination after containers were refilled with water. HCV was also associated with filter material, in which around 10% of the viral inoculum was detectable.
conclusionsThis study demonstrates the potential risk of HCV transmission among injection drug users who share water, filters, and water containers and will help to define public health interventions to reduce HCV transmission.
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