ArticleHypertension (Dallas, Tex. : 1979)2013
Outcome-driven thresholds for home blood pressure measurement: international database of home blood pressure in relation to cardiovascular outcome.
Article in Hypertension (Dallas, Tex. : 1979), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 51 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed, 6 syntheses or guidelines pooled it, 118 citations in OpenAlex.
- Brazilian Guidelines for In-office and Out-of-office Blood Pressure Measurement - 2023.Arquivos brasileiros de cardiologia · 2024Guideline
- The International Database of Central Arterial Properties for Risk Stratification: Research Objectives and Baseline Characteristics of Participants.American journal of hypertension · 2022Pooled it
- Recent status of self-measured home blood pressure in the Japanese general population: a modern database on self-measured home blood pressure (MDAS).Hypertension research : official journal of the Japanese Society of Hypertension · 2020Pooled it
- The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019).Hypertension research : official journal of the Japanese Society of Hypertension · 2019Guideline
- Is antihypertensive treatment based on home blood pressure recommended rather than that based on office blood pressure in adults with essential hypertension? (meta-analysis).Hypertension research : official journal of the Japanese Society of Hypertension · 2019Pooled it
- Risk stratification by self-measured home blood pressure across categories of conventional blood pressure: a participant-level meta-analysis.PLoS medicine · 2014Pooled it
- Evening home pulse pressure predicted cardiovascular events and mortality in older adults with hypertension: findings based on the STEP trial.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Trial
- Effects of low-intensity isometric handgrip training on home blood pressure in hypertensive patients: a randomized controlled trial.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Trial
- Effects of Isometric Handgrip Training on Home Blood Pressure Measurements in Hypertensive Patients: A Randomized Crossover Study.Internal medicine (Tokyo, Japan) · 2021Trial
- Predictive power of home blood pressure indices at baseline and during follow-up in hypertensive patients: HOMED-BP study.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Trial
- Reproducibility of masked hypertension among adults 30 years or older.Blood pressure monitoring · 2014Trial
- Agreement between seven-day and fourteen-day home systolic blood pressure stability scores: A J-HOP study analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Reassessing home blood pressure thresholds: clinical implications of lowering the diagnostic criteria to 130/80 mmHg.Journal of hypertension · 2026Article
- Divergent recommendations for home blood pressure measurement in Japanese and international hypertension guidelines.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Comparison of the associations between office and home BP with placenta-mediated pregnancy complications: the BOSHI study.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- The Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025).Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- The HOPE Asia Network consensus on blood pressure measurements corresponding to office measurements: Automated office, home, and ambulatory blood pressures.Journal of clinical hypertension (Greenwich, Conn.) · 2024Review
- In-office and out-of-office blood pressure measurement.Journal of human hypertension · 2024Review
- When and how to use ambulatory blood pressure monitoring and home blood pressure monitoring for managing hypertension.Clinical hypertension · 2024Review
- Ethnicity-specific blood pressure thresholds based on cardiovascular and renal complications: a prospective study in the UK Biobank.BMC medicine · 2024Article
Corrections and comments
- Erratum issuedHänninen, M R [removed]
Authors and funding
15 authors at 3 institutions in 3 countries.
Funding
Abstract
The lack of outcome-driven operational thresholds limits the clinical application of home blood pressure (BP) measurement. Our objective was to determine an outcome-driven reference frame for home BP measurement. We measured home and clinic BP in 6470 participants (mean age, 59.3 years; 56.9% women; 22.4% on antihypertensive treatment) recruited in Ohasama, Japan (n=2520); Montevideo, Uruguay (n=399); Tsurugaya, Japan (n=811); Didima, Greece (n=665); and nationwide in Finland (n=2075). In multivariable-adjusted analyses of individual subject data, we determined home BP thresholds, which yielded 10-year cardiovascular risks similar to those associated with stages 1 (120/80 mm Hg) and 2 (130/85 mm Hg) prehypertension, and stages 1 (140/90 mm Hg) and 2 (160/100 mm Hg) hypertension on clinic measurement. During 8.3 years of follow-up (median), 716 cardiovascular end points, 294 cardiovascular deaths, 393 strokes, and 336 cardiac events occurred in the whole cohort; in untreated participants these numbers were 414, 158, 225, and 194, respectively. In the whole cohort, outcome-driven systolic/diastolic thresholds for the home BP corresponding with stages 1 and 2 prehypertension and stages 1 and 2 hypertension were 121.4/77.7, 127.4/79.9, 133.4/82.2, and 145.4/86.8 mm Hg; in 5018 untreated participants, these thresholds were 118.5/76.9, 125.2/79.7, 131.9/82.4, and 145.3/87.9 mm Hg, respectively. Rounded thresholds for stages 1 and 2 prehypertension and stages 1 and 2 hypertension amounted to 120/75, 125/80, 130/85, and 145/90 mm Hg, respectively. Population-based outcome-driven thresholds for home BP are slightly lower than those currently proposed in hypertension guidelines. Our current findings could inform guidelines and help clinicians in diagnosing and managing patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.