ArticleJournal of biophotonics2014
Coupled external cavity photonic crystal enhanced fluorescence.
Article in Journal of biophotonics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- Photonic Crystal Enhanced Fluorescence: A Review on Design Strategies and Applications.Micromachines · 2023Review
- Recent Advances in Biosensing With Photonic Crystal Surfaces: A Review.IEEE sensors journal · 2016Article
- Label-Free Biosensor Imaging on Photonic Crystal Surfaces.Sensors (Basel, Switzerland) · 2015Review
- Enhanced fluorescence emission using a photonic crystal coupled to an optical cavity.Applied physics letters · 2013Article
- Nanostructured surfaces and detection instrumentation for photonic crystal enhanced fluorescence.Sensors (Basel, Switzerland) · 2013Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
We report a fundamentally new approach to enhance fluorescence in which surface adsorbed fluorophore-tagged biomolecules are excited on a photonic crystal surface that functions as a narrow bandwidth and tunable mirror of an external cavity laser. This scheme leads to ∼10× increase in the electromagnetic enhancement factor compared to ordinary photonic crystal enhanced fluorescence. In our experiments, the cavity automatically tunes its lasing wavelength to the resonance wavelength of the photonic crystal, ensuring optimal on-resonance coupling even in the presence of variable device parameters and variations in the density of surface-adsorbed capture molecules. We achieve ∼10(5) × improvement in the limit of detection of a fluorophore-tagged protein compared to its detection on an unpatterned glass substrate. The enhanced fluorescence signal and easy optical alignment make cavity-coupled photonic crystals a viable approach for further reducing detection limits of optically-excited light emitters that are used in biological assays.
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Registered trials
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