ArticlePlant & cell physiology2012
Circadian clock regulates dynamic chromatin modifications associated with Arabidopsis CCA1/LHY and TOC1 transcriptional rhythms.
Article in Plant & cell physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 47 citations in OpenAlex.
- Unveiling previously undescribed circadian clock regulators and action mechanisms via TurboID-based profiling of the LWD1 interactome inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Integrated 3D genome, epigenome and transcriptome analyses reveal transcriptional coordination of circadian rhythm in rice.Nucleic acids research · 2023Article
- Variations in Circadian Clock Organization & Function: A Journey from Ancient to Recent.Planta · 2022Review
- Cryptochromes and the Circadian Clock: The Story of a Very Complex Relationship in a Spinning World.Genes · 2021Review
- TheGenes · 2021Article
- Malaria parasites regulate intra-erythrocytic development duration via serpentine receptor 10 to coordinate with host rhythms.Nature communications · 2020Article
- Diurnal regulation of SDG2 and JMJ14 by circadian clock oscillators orchestrates histone modification rhythms in Arabidopsis.Genome biology · 2019Article
- Interactive roles of chromatin regulation and circadian clock function in plants.Genome biology · 2019Review
- The Plant Circadian Oscillator.Biology · 2019Review
- NPR1 and Redox Rhythmx: Connections, between Circadian Clock and Plant Immunity.International journal of molecular sciences · 2019Review
- TheFrontiers in plant science · 2019Article
- The LDL1/2-HDA6 Histone Modification Complex Interacts With TOC1 and Regulates the Core Circadian Clock Components inFrontiers in plant science · 2019Article
- A Novel Loop: Mutual Regulation Between Epigenetic Modification and the Circadian Clock.Frontiers in plant science · 2019Review
- Review
- The Arabidopsis LDL1/2-HDA6 histone modification complex is functionally associated with CCA1/LHY in regulation of circadian clock genes.Nucleic acids research · 2018Article
- The HAF2 protein shapes histone acetylation levels of PRR5 and LUX loci in Arabidopsis.Planta · 2018Article
- Heterologous protein-DNA interactions lead to biased allelic expression of circadian clock genes in interspecific hybrids.Scientific reports · 2017Article
- Parallel analysis ofOpen biology · 2017Article
- Making the clock tick: the transcriptional landscape of the plant circadian clock.F1000Research · 2017Review
- Real-time monitoring of PtaHMGB activity in poplar transactivation assays.Plant methods · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Circadian clocks enable organisms to adapt to a 24 h diurnal cycle and anticipate rhythmic changes in the environment. The Arabidopsis central oscillator contains three genes encoding core clock components. CIRCADIAN CLOCK ASSOCIATED 1 (CCA1)/LATE ELONGATED HYPOCOTYL (LHY) and TIMING OF CAB EXPRESSION 1 (TOC1) reciprocally repress genes encoding each other and are critical for the generation of circadian rhythms controlling many clock outputs. A precise regulation of transcriptional events is, therefore, essential for proper circadian function. Here, we investigated histone 3 (H3) tail modifications of CCA1, LHY and TOC1 under various conditions. We found specific association of only H3K4Me3 and H3K9/14Ac with the translational start site of these three genes. These H3 marks were enriched at circadian time points of their increased transcription at different photoperiods and under free-running conditions, suggesting circadian regulation of H3 modifications. Analysis of clock-compromised CCA1-overexpressing lines provided evidence that light/dark photoperiods signal the establishment of these chromatin changes which are gated by the clock.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.