ArticleJournal of the mechanical behavior of biomedical materials2013
Deformationally dependent fluid transport properties of porcine coronary arteries based on location in the coronary vasculature.
Article in Journal of the mechanical behavior of biomedical materials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Finite element model predicts micromotion-induced strain profiles that correlate with the functional performance of Utah arrays in humans and non-human primates.Journal of neural engineering · 2025Article
- Improving the hemocompatibility of a porohyperelastic layered vascular graft using luminal reversal microflows.Journal of the mechanical behavior of biomedical materials · 2024Article
- Mechanical alterations of electrospun poly(ϵ-caprolactone) in response to convective thermobonding.Journal of biomedical materials research. Part B, Applied biomaterials · 2023Article
- Linking the region-specific tissue microstructure to the biaxial mechanical properties of the porcine left anterior descending artery.Acta biomaterialia · 2022Article
- A Finite Element Model for Mixed Porohyperelasticity with Transport, Swelling, and Growth.PloS one · 2016Article
- Biomechanical Comparison of Glutaraldehyde-Crosslinked Gelatin Fibrinogen Electrospun Scaffolds to Porcine Coronary Arteries.Journal of biomechanical engineering · 2016Article
- Computationally Optimizing the Compliance of a Biopolymer Based Tissue Engineered Vascular Graft.Journal of biomechanical engineering · 2016Article
- Ex vivo multiscale quantitation of skin biomechanics in wild-type and genetically-modified mice using multiphoton microscopy.Scientific reports · 2015Article
- A finite element study on variations in mass transport in stented porcine coronary arteries based on location in the coronary arterial tree.Journal of biomechanical engineering · 2013Article
- Location-dependent coronary artery diffusive and convective mass transport properties of a lipophilic drug surrogate measured using nonlinear microscopy.Pharmaceutical research · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveUnderstanding coronary artery mass transport allows researchers to better comprehend how drugs or proteins move through, and deposit into, the arterial wall. Characterizing how the convective component of transport changes based on arterial location could be useful to better understand how molecules distribute in different locations in the coronary vasculature. METHODS AND
resultsWe measured the mechanical properties and wall fluid flux transport properties of de-endothelialized (similar to post-stenting or angioplasty) left anterior descending (LADC) and right (RC) porcine coronary arteries along their arterial lengths. Multiphoton microscopy was used to determine microstructural differences. Proximal LADC regions had a higher circumferential stiffness than all other regions. Permeability decreased by 198% in the LADC distal region compared to other LADC regions. The RC artery showed a decrease of 46.9% from the proximal to middle region, and 51.7% from the middle to distal regions. The porosity increased in the intima between pressure states, without differences through the remainder of the arterial thickness.
conclusionsWe showed that the permeabilities and mechanical properties do vary in the coronary vasculature. With variations in mechanical properties, overexpansion of stents can occur more easily while variations in permeability may lead to altered transport based on location.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.