Evidence map›Paper›PMID 23127336›Full record

ArticleChemistry and physics of lipids2012

Studies of mixed liposomes with novel sorbyl functionalized head group lipids.

Saliya N Ratnayaka, El Hadj Elandaloussi, Bryan D Korth, Robert B Bates, Jeffrey Pyun, Henry K Hall, S Scott Saavedra

Open access · greenAbstract read
In one paragraph

Article in Chemistry and physics of lipids, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Saliya N RatnayakaDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721-0041, United States. saliya@arizona.edu
El Hadj Elandaloussi
Bryan D Korth
Robert B Bates
Jeffrey Pyun
Henry K Hall
S Scott Saavedra
University of Arizona · US

Funding

Sniffer Biosensors Based on Ion Channel-GPCR Chimeras and Polylipid MembranesR01EB007047 · NIBIB · UNIVERSITY OF ARIZONA · PI ASPINWALL, CRAIG A, SAAVEDRA, STEVEN SCOTT · 2006 to 2015
$3.5M
NIBIB NIH HHS EB007047NIBIB NIH HHS R01 EB007047
6 · The paper itself

Abstract

Three novel polymerizable amphiphiles with a sorbyl-substituted head group were synthesized and systematically characterized. These amphiphiles are neutral in charge. None of these molecules forms vesicles by itself, presumably due to lack of amphiphilicity and/or extensive head group interaction. Therefore, mixed vesicles were formed with other fluid lipids such as DPenPC, eggPC, or DOPC. We investigated the properties of these mixtures in both vesicles and Langmuir films. The Langmuir isotherms show formation of monolayers by all three molecules. However, the isotherms for mixed monolayers suggest that two components are largely immiscible to the mixing lipid. Under polymerization conditions, mixed vesicles of these amphiphiles form oligomers, suggesting that in spite of a larger head group, they form mesophases.

Indexed as

DiglyceridesLiposomesPhase TransitionPhosphatidylcholinesPolymerizationPropanolaminesTransition TemperatureUltraviolet Rays1,2-oleoylphosphatidylcholine1,2-pentadecanoylphosphatidylcholineDiglyceridesLiposomesPhosphatidylcholinesPropanolamines

Identifiers

PMID23127336
PMCPMC3534896
OpenAlexW2074496885

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.