Evidence map›Paper›PMID 23126575›Full record

SynthesisActa orthopaedica2012

Early proximal migration of cups is associated with late revision in THA: a systematic review and meta-analysis of 26 RSA studies and 49 survivalstudies.

Bart G Pijls, Marc J Nieuwenhuijse, Marta Fiocco, Josepha Wm Plevier, Saskia Middeldorp, Rob Ghh Nelissen, Edward R Valstar

3 registry-linked trialsAbstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Acta orthopaedica, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 99 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04017533 nacompletednot on this mapstarted 2021, after this paper: background citation

In Vivo Stability of an Uncemented Total Knee Arthroplasty With Medially Stabilized Design

TypeinterventionalSponsorOslo University HospitalRan2021 to 2024Enrolled31ConditionsKnee OsteoarthritisArmsGMK Sphere TKR
NCT04039984 nawithdrawnnot on this mapstarted 2019, after this paper: background citation

Prospective Evaluation of Fixation of the Prime Acetabular Cup

TypeinterventionalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2019 to 2022Enrolled0ConditionsOsteoarthritis, HipArmsPrime Cup
NCT06499038 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Migration Analysis of a Hybrid Hip Replacement Evaluating Stem and Ancillary Acetabular Screw Fixation-A Randomized Controlled CT-RSA Trial

TypeinterventionalSponsorHelse Møre og Romsdal HFRan2024 to 2028Enrolled60ConditionsHip OsteoarthritisArmsTotal Hip Arthroplasty
3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  14. Acetabular cup fixation with and without screws following primary total hip arthroplasty: migration evaluated by radiostereometric analysis.Hip international : the journal of clinical and experimental research on hip pathology and therapy · 2024
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39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bart G PijlsDepartment of Orthopaedics, Bio-Imaging Group, Leiden University Medical Center, Leiden, the Netherlands. b.g.c.w.pijls@lumc.nl
Marc J Nieuwenhuijse
Marta Fiocco
Josepha Wm Plevier
Saskia Middeldorp
Rob Ghh Nelissen
Edward R Valstar

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe association between excessive early migration of acetabular cups and late aseptic revision has been scantily reported. We therefore performed 2 parallel systematic reviews and meta-analyses to determine the association between early migration of acetabular cups and late aseptic revision.

methodsOne review covered early migration data from radiostereometric analysis (RSA) studies, while the other focused on revision rates for aseptic loosening from long-term survival studies. Thresholds for acceptable and unacceptable migration were classified according the Swedish Hip Arthroplasty Register and the Australian National Joint Replacement Registry: < 5% revision at 10 years.

resultsFollowing an elaborate literature search, 26 studies (involving 700 cups) were included in the RSA review and 49 studies (involving 38,013 cups) were included in the survival review. For every mm increase in 2-year proximal migration, there was a 10% increase in revision rate, which remained after correction for age, sex, diagnosis, hospital type, continent, and study quality. Consequently, proximal migration of up to 0.2 mm was considered acceptable and proximal migration of 1.0 mm or more was considered unacceptable. Cups with proximal migration of between 0.2 and 1.0 mm were considered to be at risk of having revision rates higher than 5% at 10 years.

interpretationThere was a clinically relevant association between early migration of acetabular cups and late revision due to loosening. The proposed migration thresholds can be implemented in a phased evidence-based introduction, since they allow early detection of high-risk cups while exposing a small number of patients.

Indexed as

Hip ProsthesisProsthesis DesignProsthesis FailureAgedAge FactorsArthroplasty, Replacement, HipEvidence-Based MedicineFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedNetherlandsReoperationRisk Assessment

Identifiers

PMID23126575
PMCPMC3555453

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.