ArticleJournal of the American Geriatrics Society2012
Residential proximity to nearest major roadway and cognitive function in community-dwelling seniors: results from the MOBILIZE Boston Study.
Article in Journal of the American Geriatrics Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effects of neighborhood built environment on cognitive function in older adults: a systematic review.BMC geriatrics · 2024Pooled it
- Exposure to Air Pollution in Relation to Risk of Dementia and Related Outcomes: An Updated Systematic Review of the Epidemiological Literature.Environmental health perspectives · 2021Pooled it
- Air Pollution and Dementia: A Systematic Review.Journal of Alzheimer's disease : JAD · 2019Pooled it
- Exposure to air pollution as a potential contributor to cognitive function, cognitive decline, brain imaging, and dementia: A systematic review of epidemiologic research.Neurotoxicology · 2016Pooled it
- Ambient air pollution and neurotoxicity on brain structure: Evidence from women's health initiative memory study.Annals of neurology · 2015Trial
- Effect of Environment on the Cognition of Older Adults: A Narrative Review.Brain sciences · 2026Review
- A critical review of potential modifiers of air pollutant associations with dementia and related outcomes.Neurotoxicology · 2026Review
- Air pollution and depression symptoms in middle-aged and older adults in Los Angeles County.International archives of occupational and environmental health · 2025Article
- Cognitive Performance and Long-term Exposure to Outdoor Air Pollution: Findings From the Harmonized Cognitive Assessment Protocol Substudy of the English Longitudinal Study of Ageing (ELSA-HCAP).The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Effects of particulate air pollution exposure on lung-brain axis and related miRNAs modulation in mouse models.Frontiers in cell and developmental biology · 2025Review
- Cluster pattern analysis of environmental stressors and quantifying their impact on all-cause mortality in Belgium.BMC public health · 2024Article
- Exposure to residential traffic and trajectories of unhealthy ageing: results from a nationally-representative cohort of older adults.Environmental health : a global access science source · 2024Article
- Association of Long-term Exposure to Air Pollution and Dementia Risk: The Role of Homocysteine, Methionine, and Cardiovascular Burden.Neurology · 2023Article
- The link between cognitive health and neighbourhood: perceptions of the public, and of policy-makers, about problems and solutions.BMC public health · 2023Article
- Relationships of Residential Distance to Major Traffic Roads with Dementia Incidence and Brain Structure Measures: Mediation Role of Air Pollution.Health data science · 2023Article
- Associations Between Ambient Air Pollution and Cognitive Abilities from Midlife to Early Old Age: Modification by APOE Genotype.Journal of Alzheimer's disease : JAD · 2023Article
- APOE alleles are associated with sex-specific structural differences in brain regions affected in Alzheimer's disease and related dementia.PLoS biology · 2022Article
- Road traffic noise and cognitive function in older adults: a cross-sectional investigation of The Irish Longitudinal Study on Ageing.BMC public health · 2021Article
- Ambient particulate matter, ozone, and neurologic symptoms in U.S. Gulf states adults.Environmental epidemiology (Philadelphia, Pa.) · 2021Article
- Associations between air pollution indicators and prevalent and incident diabetes in an African American cohort, the Jackson Heart Study.Environmental epidemiology (Philadelphia, Pa.) · 2021Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectivesTo evaluate the association between residential distance to nearest major roadway, as a marker of long-term exposure to traffic pollution, and cognitive function in older adults.
designProspective cohort study with median follow-up of 16.8 months.
settingCommunity.
participantsSeven hundred sixty-five community-dwelling seniors. MEASUREMENTS: The Mini-Mental State Examination, Hopkins Verbal Learning Test-Revised (HVLT-R), Trail Making Test (TMT), category and letter fluency tests, and Clock-in-the-Box Test were administered during home visits on two occasions. The residential distance to the nearest major roadway was calculated, and generalized estimating equations were used to evaluate the association between performance on each test and residential distance to nearest major roadway, adjusting for participant demographics, education, socioeconomic status, and past medical history.
resultsShorter distance to major roadway was associated with statistically significantly poorer performance on the immediate and delayed recall components of the HVLT-R, TMT Part B, TMT delta, and letter and category fluency tests. Generally, participants residing less than 100 m from a major roadway performed worst. Performance improved monotonically with increasing distance.
conclusionIn this cohort of community-dwelling older adults, residential proximity to a major roadway was associated with poorer performance on cognitive tests of verbal learning and memory, psychomotor speed, language, and executive functioning. If causal, these results add to the growing evidence that living near major roadways is associated with adverse health outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.