Trial reportPhotodermatology, photoimmunology & photomedicine2012
The effect of ultraviolet radiation from a novel portable fluorescent lamp on serum 25-hydroxyvitamin D3 levels in healthy adults with Fitzpatrick skin types II and III.
Trial report in Photodermatology, photoimmunology & photomedicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01930539 (Treatment of Vitamin D Deficiency in Intestinal Rehabilitation Clinic Patients With a Portable Ultraviolet B Lamp), which is not on this map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Treatment of Vitamin D Deficiency in Intestinal Rehabilitation Clinic Patients With a Portable Ultraviolet B Lamp
Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Review
- Review
- Low dose ultraviolet B irradiation at 308 nm with light-emitting diode device effectively increases serum levels of 25(OH)D.Scientific reports · 2021Article
- Acute Ultraviolet Light Exposure and Post-Resistance Exercise Serum Testosterone: A Pilot Study in Older Men.International journal of exercise science · 2020Article
- Ultraviolet B Light Emitting Diodes (LEDs) Are More Efficient and Effective in Producing Vitamin DScientific reports · 2017Article
- The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention.Reviews in endocrine & metabolic disorders · 2017Review
- New Approach to Develop Optimized Sunscreens that Enable Cutaneous Vitamin D Formation with Minimal Erythema Risk.PloS one · 2016Article
- Vitamin D for health: a global perspective.Mayo Clinic proceedings · 2013Article
- Sunlight and Vitamin D: A global perspective for health.Dermato-endocrinology · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
background/purposeUltraviolet (UV) B irradiation may provide a safe and effective method to treat vitamin D deficiency. The objective of this study was to assess the effectiveness of a novel Sperti D/UV-Fluorescent lamp in converting 7-dehydrocholesterol (7-DHC) to previtamin D(3) in vitro and in raising serum 25-hydroxyvitamin D(3) [25(OH)D(3) ] in healthy adults.
methodsThe lamp was assessed in vitro using a 7-DHC solution and a human skin sample. In a prospective cohort study, five healthy adults with skin types II and III were exposed to a 0.75 minimal erythemal dose of UV radiation over ≈ 9% of body surface area three times a week for 4 weeks. The main outcomes were percentage of conversion from 7-DHC to previtamin D(3) in vitro and changes in serum 25(OH)D(3) after irradiation in vivo.
resultsA dose response between UV irradiation time and conversion of 7-DHC to previtamin D(3) was seen in the 7-DHC solution and surgically obtained human skin. The subjects had a significant increase in mean 25(OH)D(3) from 18.4 ± 8.2 to 27.3 ± 7.6 ng/ml (P < 0.001) after 4 weeks of irradiation. No adverse events occurred.
conclusionThe Sperti D/UV-Fluorescent lamp is effective in converting 7-DHC to previtamin D(3) in vitro and in raising serum 25(OH)D(3) in healthy adults.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.