Evidence map›Paper›PMID 23125200›Full record

ReviewCold Spring Harbor perspectives in medicine2012

Supramolecular dynamics of mucus.

Pedro Verdugo

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Deswelling Dynamics of Chemically-Active Polyelectrolyte Gels.Computational Science--ICCS ... : international conference ... : proceedings. ICCS · 2023
    Article
  6. Article
  7. Review
  8. Mucins and CFTR: Their Close Relationship.International journal of molecular sciences · 2022
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Mucus.Current biology : CB · 2021
    Article
  15. Biophysical determinants of biofilm formation in the gut.Current opinion in biomedical engineering · 2021
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Pedro VerdugoFriday Harbor Laboratories, University of Washington, Friday Harbor, 98250, USA. verdugo@u.washington.edu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our purpose here is not to address specific issues of mucus pathology, but to illustrate how polymer networks theory and its remarkable predictive power can be applied to study the supramolecular dynamics of mucus. Avoiding unnecessary mathematical formalization, in the light of available theory, we focus on the rather slow progress and the still large number of missing gaps in the complex topology and supramolecular dynamics of airway mucus. We start with the limited information on the polymer physics of respiratory mucins to then converge on the supramolecular organization and resulting physical properties of the mucus gel. In each section, we briefly discuss progress on the subject, the uncertainties associated with the established knowledge, and the many riddles that still remain.

Indexed as

Molecular ConformationGelsHumansHydrophobic and Hydrophilic InteractionsKineticsMucinsMucusPhase TransitionPolymersRespiratory SystemGelsMucinsPolymers

Identifiers

PMID23125200
PMCPMC3543103

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.