Trial reportAJNR. American journal of neuroradiology2013
A DSA-based method using contrast-motion estimation for the assessment of the intra-aneurysmal flow changes induced by flow-diverter stents.
Trial report in AJNR. American journal of neuroradiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05526352 (@neurIST), which is not on this map. Cited by 37 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
@neurIST : Informatique biomédicale intégrée Pour la Gestion Des anévrismes cérébraux
Who cites it
37 citing papers in PubMed, 97 citations in OpenAlex.
- Comparison of intra-aneurysmal flow modification using optical flow imaging to evaluate the performance of Evolve and Pipeline flow diverting stents.Journal of neurointerventional surgery · 2020Trial
- Hemodynamic Characteristics in Ruptured and Unruptured Intracranial Aneurysms: A Prospective Cohort Study Utilizing the AneurysmFlow Tool.AJNR. American journal of neuroradiology · 2025Article
- Modeling Fibrin Accumulation on Flow-Diverting Devices for Intracranial Aneurysms.International journal for numerical methods in biomedical engineering · 2024Article
- Experimental study using phantom models of cerebral aneurysms and 4D-DSA to measure blood flow on 3D-color-coded images.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Article
- Fluid dynamics in intracranial aneurysms treated with flow-diverting stents: effect of multiple geometrical parameters.Journal of fluid mechanics · 2023Article
- Integrating computational fluid dynamics data into medical image visualization workflows via DICOM.International journal of computer assisted radiology and surgery · 2022Article
- Rupture of an adjacent cerebral aneurysm following the deployment of a Pipeline embolization device: illustrative case.Journal of neurosurgery. Case lessons · 2022Article
- "Trapped labelled spins"-related signal on arterial spin labelling in the assessment of flow-diverted aneurysms: preliminary experience.Neuroradiology · 2022Article
- Critical Angiographic and Sonographic Analysis of Intra Aneurysmal and Downstream Hemodynamic Changes After Flow Diversion.Frontiers in neurology · 2022Article
- Evaluation of Outcome Prediction of Flow Diversion for Intracranial Aneurysms.AJNR. American journal of neuroradiology · 2021Article
- Mathematical Models for Blood Flow Quantification in Dialysis Access Using Angiography: A Comparative Study.Diagnostics (Basel, Switzerland) · 2021Article
- Evaluation of methods to derive blood flow velocity from 1000 fps high-speed angiographic sequences (HSA) using optical flow (OF) and computational fluid dynamics (CFD).Proceedings of SPIE--the International Society for Optical Engineering · 2021Article
- The Cascade device - In vitro tests to assess coil protrusion into the parent vessel.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2020Article
- Angiographic assessment of the efficacy of flow diverter treatment for cerebral aneurysms.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2019Article
- How Flow Reduction Influences the Intracranial Aneurysm Occlusion: A Prospective 4D Phase-Contrast MRI Study.AJNR. American journal of neuroradiology · 2019Article
- Analysis of Flow Dynamics and Outcomes of Cerebral Aneurysms Treated with Intrasaccular Flow-Diverting Devices.AJNR. American journal of neuroradiology · 2019Article
- Image-based modeling of blood flow in cerebral aneurysms treated with intrasaccular flow diverting devices.International journal for numerical methods in biomedical engineering · 2019Article
- On Flow Diversion: The Changing Landscape of Intracerebral Aneurysm Management.AJNR. American journal of neuroradiology · 2019Review
- Quantification of Blood Velocity with 4D Digital Subtraction Angiography Using the Shifted Least-Squares Method.AJNR. American journal of neuroradiology · 2018Article
- In vitro angiographic comparison of the flow-diversion performance of five neurovascular stents.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2018Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeFlow-diverter stents modify intra-aneurysmal blood flow and induce the progressive thrombosis of intracranial aneurysms followed by stable vascular reconstruction. The aim of this study was to report a new method for the appraisal of intracranial blood flow from DSA performed during endovascular treatment procedures. MATERIALS AND
methodsA cohort of 24 patients with unruptured IAs who underwent FDS implantation was prospectively recruited. Pre- and post-DSA sequences in combination with 3D rotational angiography were acquired. The quantification of arterial and intra-aneurysmal flow was accomplished by using an optical flow approach. Flow reduction was assessed by using a new metric termed the mean aneurysm flow amplitude ratio. The correlation between the MAFA ratio and the incidence of aneurysm thrombosis was assessed by using receiver operating characteristic analysis and the Fisher exact test when the optimum Youden index was found.
resultsThe quantification of flow was successfully achieved in 21 of 24 patients (87.5%). On the imaging follow-up, 18 aneurysms developed complete thrombosis (87.5%) and 3 displayed residual circulation (12.5%). The threshold analysis of the MAFA ratio significantly predicted thrombosis at 12 months below a threshold of 1.03 (P=.035). There was no significant correlation between the time for complete occlusion of the aneurysm and contrast stagnation inside the aneurysm after treatment (P>.05).
conclusionsThe MAFA ratio based on DSA flow quantification appears to be a reliable predictor for the assessment of stent treatment outcomes in this small study. These results open the door for perioperative flow quantification and provide indices that may help clinicians make appropriate intraprocedural decisions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.