SynthesisClinical neuroradiology2012
Pipeline embolization device for intracranial aneurysm: a systematic review.
Synthesis in Clinical neuroradiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Outcomes following surgical and endovascular treatment of extracranial vertebral artery aneurysms (VAA): a systematic evaluation of the literature.Neurosurgical review · 2023Pooled it
- Whether Intracranial Aneurysm Could Be Well Treated by Flow Diversion: A Comprehensive Meta-Analysis of Large-Sample Studies including Anterior and Posterior Circulation.BioMed research international · 2021Pooled it
- Outcome of Flow Diverters with Surface Modifications in Treatment of Cerebral Aneurysms: Systematic Review and Meta-analysis.AJNR. American journal of neuroradiology · 2021Pooled it
- Mechanisms of Intracranial Aneurysm Rupture: An Integrative Review of Experimental and Clinical Evidence.Journal of clinical medicine · 2025Review
- Vascular Reconstruction Device for Coil Embolization of Wide-Neck Type Cerebral Aneurysm: Findings from a Post-Marketing Surveillance Study in Japan.Journal of neuroendovascular therapy · 2025Article
- Microsurgical and endovascular treatment of large and giant aneurysms of the anterior circulation: A systematic review.Brain & spine · 2024Article
- Analysis of reported adverse events of pipeline stents for intracranial aneurysms using the FDA MAUDE database.Journal of cerebrovascular and endovascular neurosurgery · 2023Article
- Pipeline versus Tubridge in the treatment of unruptured posterior circulation aneurysms.Chinese neurosurgical journal · 2023Article
- Acute Distal Migration and Shortening of the Flow-Redirection Endoluminal Device: A Case Report.Journal of neuroendovascular therapy · 2023Article
- A review of technological innovations leading to modern endovascular brain aneurysm treatment.Frontiers in neurology · 2023Review
- Global tendencies and frontier topics in hemodynamics research of intracranial aneurysms: a bibliometric analysis from 1999 to 2022.Frontiers in physiology · 2023Article
- Comparison of Pipeline Embolization and Coil Embolization for the Treatment of Large Unruptured Paraclinoid Aneurysms.Neurologia medico-chirurgica · 2022Article
- Distal migration of the flow-redirection endoluminal device immediately after treatment: A case report and literature review.Surgical neurology international · 2022Article
- The evolution of intracranial aneurysm research from 2012 to 2021: Global productivity and publication trends.Frontiers in neurology · 2022Article
- Imbalanced flow changes of distal arteries: An important factor in process of delayed ipsilateral parenchymal hemorrhage after flow diversion in patients with cerebral aneurysms.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021Article
- The Combination of Stent and Antiplatelet Therapy May Be Responsible of Parenchymal Magnetic Susceptibility Artifacts after Endovascular Procedure.Tomography (Ann Arbor, Mich.) · 2021Article
- Stent-assisted coil embolization for an unruptured vertebral artery-posterior inferior cerebellar artery aneurysm with retrograde access via type 1 persistent primitive proatlantal artery: A case report.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021Article
- Application of hybrid operating rooms for clipping large or giant intracranial carotid-ophthalmic aneurysms.World journal of clinical cases · 2020Article
- One and done? The effect of number of Pipeline embolization devices on aneurysm treatment outcomes.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2020Article
- Pipeline embolization for an iatrogenic intracranial internal carotid artery pseudoaneurysm after transsphenoidal pituitary tumor surgery: Case report and review of the literature.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe pipeline embolization device (PED) is a new endovascular stent designed for the treatment of challenging intracranial aneurysms (IAs). Its use has been extended to nonruptured and ruptured IAs of a variety of configurations and etiologies in both the anterior and posterior circulations.
methodsWe conducted a systematic review of ten eligible reports on its clinical efficacy and safety.
resultsThere were 414 patients with 448 IAs. The majority of the IAs were large (40.2 %), saccular or blister-like (78.3 %), and were located mostly in the anterior circulation (83.5 %). The regimens of antiplatelet therapy varied greatly between and within studies. The mean number of the PED used was 2.0 per IA. Deployment was successful in around 95 % of procedures. Aneurysm obliteration was achieved in 82.9 % of IAs at 6-month. The overall incidences of periprocedural intracranial vascular complication rate and mortality rate were 6.3 and 1.5 %, respectively.
conclusionThe PED is a safe and effective treatment for nonruptured IAs. Its use in the context of acute subarachnoid hemorrhage (SAH) should be cautioned. Its main limitations include the need for prolonged antiplatelet therapy, as well as the potential risks of IA rupture and non-IA-related intracerebral hemorrhages (ICH). Future studies should aim at identifying factors that predispose to incomplete obliteration, delayed rupture, and thromboembolic complications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.