ReviewCurrent opinion in virology2012
Cell-based genomic screening: elucidating virus-host interactions.
Review in Current opinion in virology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Probenecid is a dual-acting antiviral/anti-inflammatory therapy for diverse respiratory viruses.Frontiers in pharmacology · 2026Article
- Next-generation viral detection through AI-enhanced nanotechnology: advances, challenges, and future directions.Frontiers in molecular biosciences · 2026Article
- Mobilization of nuclear antiviral factors by exportin XPO1 via the actin network inhibits RNA virus replication.PLoS pathogens · 2025Article
- Functional Roles and Host Interactions ofPathogens (Basel, Switzerland) · 2025Review
- Review
- Identification of Host Factors of Paramyxoviruses by siRNA Genome-Wide Screens.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Orthogonal genome-wide screens of bat cells identify MTHFD1 as a target of broad antiviral therapy.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Advances in high-throughput methods for the identification of virus receptors.Medical microbiology and immunology · 2020Review
- Article
- Article
- Review
- Growth-restricting effects of siRNA transfections: a largely deterministic combination of off-target binding and hybridization-independent competition.Nucleic acids research · 2018Article
- Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors.Journal of visualized experiments : JoVE · 2018Article
- Defense Mechanisms against Viral Infection inViruses · 2018Review
- Genome-wide RNAi Screening to Identify Host Factors That Modulate Oncolytic Virus Therapy.Journal of visualized experiments : JoVE · 2018Article
- Identification of host DEAD-box RNA helicases that regulate cellular tropism of oncolytic Myxoma virus in human cancer cells.Scientific reports · 2017Article
- Tobacco vein banding mosaic virus 6K2 Protein Hijacks NbPsbO1 for Virus Replication.Scientific reports · 2017Article
- RNAi screen reveals a role of SPHK2 in dengue virus-mediated apoptosis in hepatic cell lines.PloS one · 2017Article
- Tetraspanin CD151 Promotes Initial Events in Human Cytomegalovirus Infection.Journal of virology · 2016Article
- Chronic hepatitis C: This and the new era of treatment.World journal of hepatology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Viruses rely on host cell machinery for successful infection, while at the same time evading the host immune response. Characterization of these processes has revealed insights both into fundamental cellular processes as well as the nuances of viral replication. The recent advent of cell-based screening coupled with RNAi technology, has greatly facilitated studies focused on characterizing the virus-host interface and has expanded our understanding of cellular factors that impact viral infection. These findings have led to the discovery of potential therapeutic targets, but there is certainly more to be discovered. In this article we will review the recent progress in this arena and discuss the challenges and future of this emerging field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.