Effects of physical inactivity on non-communicable diseases.

Carlo La Vecchia, Silvano Gallus, Silvio Garattini

Registry-linked trialAbstract readLetterComment

In one paragraph

Article in Lancet (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03654105 (Multifactorial Intervention of Primary Prevention in High Risk Subjects), which is not on this map. Cited by 6 papers.

0numbers the graph read from it

0cells of the map it votes in

6citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03654105 phase2active not recruitingnot on this mapstarted 2019, after this paper: background citation

Multifactorial Intervention of Primary Prevention in High Risk Subjects: a Randomized Trial

TypeinterventionalSponsorFondazione IRCCS Istituto Nazionale dei Tumori, MilanoRan2019 to 2026Enrolled2,000ConditionsInflammation, Smoking Cessation, Diet Modification, Physical ActivityArmsCytisine, Acetylsalicylic acid, Diet Modification and Physical Activity Increase, early lung cancer detection, spirometry with CO test

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

Sociodemographic and Lifestyle Factors Associated with Cardiovascular Risk in a Large Cohort of Spanish Workers.Rambam Maimonides medical journal · 2025
Article
A Cohort of Sociodemographic and Health-Related Risk Factors for All-Cause Mortality in Middle-Aged and Older Adults in China.Healthcare (Basel, Switzerland) · 2025
Article
The "adult inactivity triad" in patients with chronic kidney disease: A review.Frontiers in medicine · 2023
Review
COVID-19 confinement impact on weight gain and physical activity in the older adult population: Data from the LOST in Lombardia study.Clinical nutrition ESPEN · 2022
Article
Addressing the global Challenge of NCDs using a Risk Factor approach: voices from around the world.FASEB bioAdvances · 2021
Article
Progress of Clinical Trials for the Treatment of Gestational Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021
Review

4 · The record

Corrections and comments

Comment on
Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy.2012

5 · Who and what money

Authors and funding

3 authors.

Carlo La Vecchia

Silvano Gallus

Silvio Garattini

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cost of IllnessExerciseBreast NeoplasmsColonic NeoplasmsCoronary DiseaseDiabetes Mellitus, Type 2FemaleHumans

Identifiers

PMID23122239

DOI10.1016/S0140-6736(12)61872-8

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

NCT03654105ClinicalTrials.gov

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.