Evidence map›Paper›PMID 23121619›Full record

ReviewLeukemia & lymphoma2013

Advances in the biology and therapy of chronic myeloid leukemia: proceedings from the 6th Post-ASH International Chronic Myeloid Leukemia and Myeloproliferative Neoplasms Workshop.

Richard A Van Etten, Michael Mauro, Jerald P Radich, John M Goldman, Giuseppe Saglio, Catriona Jamieson, Simona Soverini, Carlo Gambacorti-Passerini, Rüdiger Hehlmann, Giovanni Martinelli and 5 more

Abstract readReview
In one paragraph

Review in Leukemia & lymphoma, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Richard A Van EttenMolecular Oncology Research Institute, Tufts Medical Center, Boston, MA 02111, USA. Rvanetten@tuftsmedicalcenter.org
Michael Mauro
Jerald P Radich
John M Goldman
Giuseppe Saglio
Catriona Jamieson
Simona Soverini
Carlo Gambacorti-Passerini
Rüdiger Hehlmann
Giovanni Martinelli
Danilo Perrotti
David T Scadden
Tomasz Skorski
Ayalew Tefferi
Tariq I Mughal

Funding

STUDIES OF BCR/ABL LEUKEMOGENESIS IN MICER01CA090576 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI VAN ETTEN, RICHARD A. · 2001 to 2021
$5.9M
Genomic instability causes imatinib resistance in CMLR01CA123014 · NCI · TEMPLE UNIV OF THE COMMONWEALTH · PI SKORSKI, TOMASZ · 2008 to 2012
$2.0M
Molecular Pathogenesis & Therapy of JAK2 V617F-induced Myeloproliferative DiseaseR01HL089747 · NHLBI · TUFTS MEDICAL CENTER · PI VAN ETTEN, RICHARD A. · 2008 to 2012
$2.0M
"BCR/ABL-PI-3k-ROS pathway induce genomic instability ...."R01CA134458 · NCI · TEMPLE UNIV OF THE COMMONWEALTH · PI SKORSKI, TOMASZ · 2010 to 2014
$1.5M
NCI NIH HHS CA0905756NCI NIH HHS CA123014NCI NIH HHS CA134458NCI NIH HHS R01 CA090576NCI NIH HHS R01 CA123014NCI NIH HHS R01 CA134458NHLBI NIH HHS R01 HL089747
6 · The paper itself

Abstract

Following the 53rd annual meeting of the American Society of Hematology (ASH) in San Diego in December 2011, a group of clinical and laboratory investigators convened for the 6th Post-ASH International Workshop on Chronic Myeloid Leukemia (CML) and Myeloproliferative Neoplasms (MPN). The Workshop took place on 13-14 December at the Estancia, La Jolla, California, USA. This report summarizes the most recent advances in the biology and therapy of CML that were presented at the ASH meeting and discussed at the Workshop. Preclinical studies focused on the CML stem cell and its niche, and on early results of deep sequencing of CML genomes. Clinical advances include updates on second- and third-generation tyrosine kinase inhibitors (TKIs), molecular monitoring, TKI discontinuation studies and new therapeutic agents. A report summarizing the pertinent advances in MPN has been published separately.

Indexed as

AnimalsAntineoplastic AgentsGenomicsHumansLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMolecular Targeted TherapyNeoplastic Stem CellsProtein Kinase InhibitorsStem Cell NicheTreatment OutcomeAntineoplastic AgentsProtein Kinase Inhibitors

Identifiers

PMID23121619
PMCPMC3612371

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.