ReviewAnnual review of physiology2013
Understanding the rhythm of breathing: so near, yet so far.
Review in Annual review of physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03903666 (Anomalies of Nocturnal Gaz Exchanges in Patients With Down Syndrome Aged From 4 to 16 Years), which is not on this map. Cited by 227 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Anomalies of Nocturnal Gaz Exchanges in Patients With Down Syndrome Aged From 4 to 16 Years
Who cites it
227 citing papers in PubMed.
- Prolonged postictal hypercapnia is associated with delayed recovery of consciousness after generalized convulsive seizure.Seizure · 2026Article
- Comparative Ion Channel Transcriptomes of NK1R and Somatostatin Neurons in the PreBötzinger Complex of the Ventrolateral Medulla.Molecular neurobiology · 2026Article
- The sneezing reflex: neurophysiology, neuroimmune pathways and clinical disorders.Acta neurologica Belgica · 2026Review
- Brainstem Circuits for Rhythm Generation and Coordination of Orofacial Movements.Annual review of neuroscience · 2026Review
- Conserved Cell Type Signatures Across the Brainstem and Spinal Cord in the Mouse Central Nervous System.bioRxiv : the preprint server for biology · 2026Article
- Astrocyte activation in the ventrolateral medulla modulates breathing and arousal states.Nature communications · 2026Article
- Respiratory pauses highlight sleep architecture in mice.Nature communications · 2026Article
- Cardiorespiratory cross-frequency coupling biomarker for sudden unexpected death in epilepsy.Epilepsia · 2026Article
- Current perspectives in sudden unexpected death in epilepsy (SUDEP): epidemiology, research approaches and pathways to prevention.Neurological research and practice · 2026Review
- Disruption of Pre-Bötzinger Complex neuropeptidergic tonality controls fear and metabolic response.bioRxiv : the preprint server for biology · 2026Article
- Rhythm generation, robustness, and control in stick insect locomotion: modeling and analysis.Journal of computational neuroscience · 2025Article
- Paraventricular nucleus neurons: important regulators of respiratory movement in mice with chronic intermittent hypoxia.Annals of medicine · 2025Article
- From Smoke to Respiratory Relief: Development, Validation and Feasibility of Pranayama-based VRBT Module for Enhancing Pulmonary Function in Biomass Smoke Exposed Women.Annals of neurosciences · 2025Article
- Association between respiratory-related cortical activation and weaning from mechanical ventilation: a physiological study.Critical care (London, England) · 2025Article
- Multimodal Breathing Control: Pontomedullary Mechanisms and Current Perspectives.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025Review
- Respiration Facilitates Behavior During Multisensory Integration.Psychophysiology · 2025Article
- A cholinergic spinal pathway for the adaptive control of breathing.Cell reports · 2025Article
- Control of breathing during hibernation in golden-mantled ground squirrels.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2025Article
- A Molecularly Defined Medullary Network for Control of Respiratory Homeostasis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- GABAergic neurons in central amygdala contribute to orchestrating anxiety-like behaviors and breathing patterns.Nature communications · 2025Article
167 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Breathing is an essential behavior that presents a unique opportunity to understand how the nervous system functions normally, how it balances inherent robustness with a highly regulated lability, how it adapts to both rapidly and slowly changing conditions, and how particular dysfunctions result in disease. We focus on recent advancements related to two essential sites for respiratory rhythmogenesis: (a) the preBötzinger Complex (preBötC) as the site for the generation of inspiratory rhythm and (b) the retrotrapezoid nucleus/parafacial respiratory group (RTN/pFRG) as the site for the generation of active expiration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.