Evidence map›Paper›PMID 23118963›Full record

ArticlePloS one2012

RETRACTED: Rickettsia species in African Anopheles mosquitoes.

Cristina Socolovschi, Frédéric Pages, Mamadou O Ndiath, Pavel Ratmanov, Didier Raoult

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecular detection and characterization ofInfection ecology & epidemiology · 2025
    Article
  4. Article
  5. Review
  6. Systematic Review on Diversity and Distribution ofPathogens (Basel, Switzerland) · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Discovery ofFrontiers in microbiology · 2022
    Article
  11. Article
  12. Crystal structure of acetoacetyl-CoA reductase from Rickettsia felis.Acta crystallographica. Section F, Structural biology communications · 2021
    Article
  13. Article
  14. Review
  15. Prevalence ofAfrican health sciences · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Parallel Decline of Malaria andThe American journal of tropical medicine and hygiene · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Cristina SocolovschiAix Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, Inserm 1095, Marseille, France.
Frédéric Pages
Mamadou O Ndiath
Pavel Ratmanov
Didier Raoult
Aix-Marseille Université · FRÉcologie Marine Tropicale des Océans Pacifique et Indien · REInstitut de Recherche pour le Développement · SNUnité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is higher rate of R. felis infection among febrile patients than in healthy people in Sub-Saharan Africa, predominantly in the rainy season. Mosquitoes possess a high vectorial capacity and, because of their abundance and aggressiveness, likely play a role in rickettsial epidemiology. METHODOLOGY/PRINCIPAL

findingsQuantitative and traditional PCR assays specific for Rickettsia genes detected rickettsial DNA in 13 of 848 (1.5%) Anopheles mosquitoes collected from Côte d'Ivoire, Gabon, and Senegal. R. felis was detected in one An. gambiae molecular form S mosquito collected from Kahin, Côte d'Ivoire (1/77, 1.3%). Additionally, a new Rickettsia genotype was detected in five An. gambiae molecular form S mosquitoes collected from Côte d'Ivoire (5/77, 6.5%) and one mosquito from Libreville, Gabon (1/88, 1.1%), as well as six An. melas (6/67, 9%) mosquitoes collected from Port Gentil, Gabon. A sequence analysis of the gltA, ompB, ompA and sca4 genes indicated that this new Rickettsia sp. is closely related to R. felis. No rickettsial DNA was detected from An. funestus, An. arabiensis, or An. gambiae molecular form M mosquitoes. Additionally, a BLAST analysis of the gltA sequence from the new Rickettsia sp. resulted in a 99.71% sequence similarity to a species (JQ674485) previously detected in a blood sample of a Senegalese patient with a fever from the Bandafassi village, Kedougou region.

conclusionR. felis was detected for the first time in An. gambiae molecular form S, which represents the major African malaria vector. The discovery of R. felis, as well as a new Rickettsia species, in mosquitoes raises new issues with respect to African rickettsial epidemiology that need to be investigated, such as bacterial isolation, the degree of the vectorial capacity of mosquitoes, the animal reservoirs, and human pathogenicity.

Indexed as

AfricaAnimalsAnophelesEntomologyFemaleGenes, BacterialHumansRickettsiaRickettsia felis

Identifiers

PMID23118963
PMCPMC3484133
OpenAlexW1978079724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.