ArticlePloS one2012
Functional and transcriptome analysis reveals an acclimatization strategy for abiotic stress tolerance mediated by Arabidopsis NF-YA family members.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers, 1 of them a synthesis that pooled it.
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Who cites it
97 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Comparative Transcriptomic Meta-Analysis Revealed Conserved Key Genes and Regulatory Networks Involved in Drought Tolerance in Cereal Crops.International journal of molecular sciences · 2021Pooled it
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- Genome-Wide Identification of theLife (Basel, Switzerland) · 2026Article
- Genome-Wide Identification of NF-YA Transcription Factors in Strawberry and Their Responses to Salt Stress.Plants (Basel, Switzerland) · 2026Article
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- Comprehensive Analysis ofPlants (Basel, Switzerland) · 2025Article
- The transcription factor NF-YA10 determines the area explored by Arabidopsis thaliana roots and directly regulates LAZY genes.The Plant journal : for cell and molecular biology · 2025Article
- Forewarned is forearmed: rice plants develop tolerance to post-anoxia during anoxic conditions by proteomic changes.Frontiers in plant science · 2025Article
- Genome-Wide Identification and Expression Analysis ofInternational journal of molecular sciences · 2024Article
- Overexpression of an NF-YB gene family member, EaNF-YB2, enhances drought tolerance in sugarcane (Saccharum Spp. Hybrid).BMC plant biology · 2024Article
- Plant Nuclear Factor Y (NF-Y) Transcription Factors: Evolving Insights into Biological Functions and Gene Expansion.International journal of molecular sciences · 2024Review
- Comparative Physiological and Transcriptomics Profiling Provides Integrated Insight into Melatonin Mediated Salt and Copper Stress Tolerance inPlants (Basel, Switzerland) · 2024Article
- Transcription factor TaNF-YB2 interacts with partners TaNF-YA7/YC7 and transcriptionally activates distinct stress-defensive genes to modulate drought tolerance in T. Aestivum.BMC plant biology · 2024Article
- Nuclear factor Y-A3b binds to theHorticulture research · 2024Article
- Transcriptome Analysis Reveals Novel Insights into the HyperaccumulatorPlants (Basel, Switzerland) · 2024Article
- Article
- Predicting yield of individual field-grown rapeseed plants from rosette-stage leaf gene expression.PLoS computational biology · 2023Article
- Crucial Abiotic Stress Regulatory Network of NF-Y Transcription Factor in Plants.International journal of molecular sciences · 2023Review
- Ammonium Uptake, Mediated by Ammonium Transporters, Mitigates Manganese Toxicity in Duckweed,Plants (Basel, Switzerland) · 2023Article
- Evolutionary insights and expression dynamics of the CaNFYB transcription factor gene family in pepper (Frontiers in genetics · 2023Article
37 more citing papers are in PubMed but not listed here.
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4 authors.
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Abstract
Nuclear Factor Y (NF-Y) is a heterotrimeric complex formed by NF-YA/NF-YB/NF-YC subunits that binds to the CCAAT-box in eukaryotic promoters. In contrast to other organisms, in which a single gene encodes each subunit, in plants gene families of over 10 members encode each of the subunits. Here we report that five members of the Arabidopsis thaliana NF-YA family are strongly induced by several stress conditions via transcriptional and miR169-related post-transcriptional mechanisms. Overexpression of NF-YA2, 7 and 10 resulted in dwarf late-senescent plants with enhanced tolerance to several types of abiotic stress. These phenotypes are related to alterations in sucrose/starch balance and cell elongation observed in NF-YA overexpressing plants. The use of transcriptomic analysis of transgenic plants that express miR169-resistant versions of NF-YA2, 3, 7, and 10 under an estradiol inducible system, as well as a dominant-repressor version of NF-YA2 revealed a set of genes, whose promoters are enriched in NF-Y binding sites (CCAAT-box) and that may be directly regulated by the NF-Y complex. This analysis also suggests that NF-YAs could participate in modulating gene regulation through positive and negative mechanisms. We propose a model in which the increase in NF-YA transcript levels in response to abiotic stress is part of an adaptive response to adverse environmental conditions in which a reduction in plant growth rate plays a key role.
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