ArticlePloS one2012
The inheritance pattern of 24 nt siRNA clusters in arabidopsis hybrids is influenced by proximity to transposable elements.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 53 citations in OpenAlex.
- Investigation of allele-specific expression in citrus hybrids reveals the association between siRNA-mediatedHorticulture research · 2026Article
- Major impacts of widespread structural variation on sorghum.Genome research · 2024Article
- The Genomic Shock Hypothesis: Genetic and Epigenetic Alterations of Transposable Elements after Interspecific Hybridization in Plants.Epigenomes · 2023Review
- Dynamic roles of small RNAs and DNA methylation associated with heterosis in allotetraploid cotton (Gossypium hirsutum L.).BMC plant biology · 2023Article
- Review
- Ectopic expression of GmHP08 enhances resistance of transgenic Arabidopsis toward drought stress.Plant cell reports · 2021Article
- Heterologous Expression of a Soybean GenePlants (Basel, Switzerland) · 2020Article
- Variation and Inheritance of Small RNAs in Maize Inbreds and F1 Hybrids.Plant physiology · 2020Article
- The Soybean GmNAC019 Transcription Factor Mediates Drought Tolerance inInternational journal of molecular sciences · 2019Article
- Ectopic Expression ofBiomolecules · 2019Article
- Unravelling the epigenomic interactions between parental inbreds resulting in an altered hybrid methylome in pigeonpea.DNA research : an international journal for rapid publication of reports on genes and genomes · 2018Article
- Recent research on the mechanism of heterosis is important for crop and vegetable breeding systems.Breeding science · 2018Review
- Epigenetic regulation of agronomical traits in Brassicaceae.Plant cell reports · 2018Review
- Parental Expression Variation of Small RNAs Is Negatively Correlated with Grain Yield Heterosis in a Maize Breeding Population.Frontiers in plant science · 2018Article
- A New Mechanism for Mendelian Dominance in Regulatory Genetic Pathways: Competitive Binding by Transcription Factors.Genetics · 2017Article
- An Arabidopsis Natural Epiallele Maintained by a Feed-Forward Silencing Loop between Histone and DNA.PLoS genetics · 2017Article
- Twenty-four-nucleotide siRNAs produce heritable trans-chromosomal methylation in F1 Arabidopsis hybrids.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Role of DNA methylation in hybrid vigor in Arabidopsis thaliana.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Methylation interactions in Arabidopsis hybrids require RNA-directed DNA methylation and are influenced by genetic variation.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Creating Order from Chaos: Epigenome Dynamics in Plants with Complex Genomes.The Plant cell · 2016Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hybrids often display increased size and growth, and thus are widely cultivated in agriculture and horticulture. Recent discoveries demonstrating the important regulatory roles of small RNAs have greatly improved our understanding of many basic biological questions, and could illuminate the molecular basis for the enhanced growth and size of hybrid plants. We profiled small RNAs by deep sequencing to characterize the inheritance patterns of small RNA levels in reciprocal hybrids of two Arabidopsis thaliana accessions, Columbia and Landsberg erecta. We find 24-nt siRNAs predominate among those small RNAs that are differentially expressed between the parents. Following hybridization, the transposable element (TE)-derived siRNAs are often inherited in an additive manner, whereas siRNAs associated with protein-coding genes are often down-regulated in hybrids to the levels observed for the parent with lower relative siRNA levels. Among the protein-coding genes that exhibit this pattern, genes that function in pathogen defense, abiotic stress tolerance, and secondary metabolism are significantly enriched. Small RNA clusters from protein-coding genes where a TE is present within one kilobase show a different predominant inheritance pattern (additive) from those that do not (low-parent dominance). Thus, down-regulation in the form of low-parent dominance is likely the default pattern of inheritance for genic siRNA, and a different inheritance mechanism for TE siRNA is suggested.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.