Evidence map›Paper›PMID 23118787›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2012

Systems biology of meridians, acupoints, and chinese herbs in disease.

Li-Ling Lin, Ya-Hui Wang, Chi-Yu Lai, Chan-Lao Chau, Guan-Chin Su, Chun-Yi Yang, Shu-Ying Lou, Szu-Kai Chen, Kuan-Hao Hsu, Yen-Ling Lai and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Recent Advance in Applications of Proteomics Technologies on Traditional Chinese Medicine Research.Evidence-based complementary and alternative medicine : eCAM · 2015
    Review
  6. The holistic effects of acupuncture treatment.Evidence-based complementary and alternative medicine : eCAM · 2014
    Article
  7. Article
  8. Article
  9. A longitudinal study of the reliability of acupuncture deqi sensations in knee osteoarthritis.Evidence-based complementary and alternative medicine : eCAM · 2013
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Li-Ling LinDepartment of Life Science, National Taiwan University, No. 1, Section 4, Roosevelt Road, Taipei 106, Taiwan.
Ya-Hui Wang
Chi-Yu Lai
Chan-Lao Chau
Guan-Chin Su
Chun-Yi Yang
Shu-Ying Lou
Szu-Kai Chen
Kuan-Hao Hsu
Yen-Ling Lai
Wei-Ming Wu
Jian-Long Huang
Chih-Hsin Liao
Hsueh-Fen Juan
National Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meridians, acupoints, and Chinese herbs are important components of traditional Chinese medicine (TCM). They have been used for disease treatment and prevention and as alternative and complementary therapies. Systems biology integrates omics data, such as transcriptional, proteomic, and metabolomics data, in order to obtain a more global and complete picture of biological activity. To further understand the existence and functions of the three components above, we reviewed relevant research in the systems biology literature and found many recent studies that indicate the value of acupuncture and Chinese herbs. Acupuncture is useful in pain moderation and relieves various symptoms arising from acute spinal cord injury and acute ischemic stroke. Moreover, Chinese herbal extracts have been linked to wound repair, the alleviation of postmenopausal osteoporosis severity, and anti-tumor effects, among others. Different acupoints, variations in treatment duration, and herbal extracts can be used to alleviate various symptoms and conditions and to regulate biological pathways by altering gene and protein expression. Our paper demonstrates how systems biology has helped to establish a platform for investigating the efficacy of TCM in treating different diseases and improving treatment strategies.

Identifiers

PMID23118787
PMCPMC3483864
OpenAlexW2112109699

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.