ArticleMarine drugs2012
New cembrane diterpenoids from a Hainan soft coral Sinularia sp.
Article in Marine drugs, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The trial behind it
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Who cites it
7 citing papers in PubMed, 26 citations in OpenAlex.
- SMART-Guided Isolation and Identification of Seven-Membered Cembranolides with Anti-Inflammation Activity from the Soft CoralMarine drugs · 2025Article
- Structurally diverse polyketides and phenylspirodrimanes from the soft coral-associated fungus Stachybotrys chartarum SCSIO41201.The Journal of antibiotics · 2021Article
- Coral and Coral-Associated Microorganisms: A Prolific Source of Potential Bioactive Natural Products.Marine drugs · 2019Review
- Sinulolides A-H, new cyclopentenone and butenolide derivatives from soft coral Sinularia sp.Marine drugs · 2014Article
- Bioactive cembranoids, sarcocrassocolides P-R, from the Dongsha Atoll soft coral Sarcophyton crassocaule.Marine drugs · 2014Article
- New sinularianin sesquiterpenes from soft coral Sinularia sp.Marine drugs · 2013Article
- 5-Episinuleptolide acetate, a norcembranoidal diterpene from the formosan soft coral Sinularia sp., induces leukemia cell apoptosis through Hsp90 inhibition.Molecules (Basel, Switzerland) · 2013Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Five new cembrane diterpenoids, named sinuflexibilins A-E (1-5), along with nine other known diterpenoids (6-14), have been isolated from the organic extract of a Hainan soft coral Sinularia sp. Their structures were determined on the basis of extensive spectroscopic analyses and by comparison of their spectral data with those of related metabolites. Compound 13, flexibilide, exhibited significant inhibitory activity of NF-κB activation using the cell-based HEK293 NF-κB luciferase reporter gene assay.
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Registered trials
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