Evidence map›Paper›PMID 23118242›Full record

GuidelinePediatrics2012

A practice pathway for the identification, evaluation, and management of insomnia in children and adolescents with autism spectrum disorders.

Beth A Malow, Kelly Byars, Kyle Johnson, Shelly Weiss, Pilar Bernal, Suzanne E Goldman, Rebecca Panzer, Daniel L Coury, Dan G Glaze, Sleep Committee of the Autism Treatment Network

Open access · bronzeAbstract readPractice GuidelineSystematic Review
In one paragraph

Guideline in Pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 7 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 7 syntheses or guidelines pooled it, 275 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Pooled it
  6. Guideline
  7. Guideline
  8. Randomized Behavioral Sleep Clinical Trial to Improve Outcomes in Children With Down Syndrome.American journal on intellectual and developmental disabilities · 2022
    Trial
  9. Trial
  10. A Randomized, Crossover Trial of a Novel Sound-to-Sleep Mattress Technology in Children with Autism and Sleep Difficulties.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2017
    Trial
  11. Parent-based sleep education for children with autism spectrum disorders.Journal of autism and developmental disorders · 2014
    Trial
  12. Article
  13. Review
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  15. Review
  16. Article
  17. Article
  18. Article
  19. Genomic dissection of sleep archetypes in a large autism cohort.medRxiv : the preprint server for health sciences · 2025
    Article
  20. Review

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 2 countries.

Beth A MalowDepartments of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA. beth.malow@vanderbilt.edu
Kelly Byars
Kyle Johnson
Shelly Weiss
Pilar Bernal
Suzanne E Goldman
Rebecca Panzer
Daniel L Coury
Dan G Glaze
Sleep Committee of the Autism Treatment Network
Baylor College of Medicine · USCincinnati Children's Hospital Medical Center · USHolland Bloorview Kids Rehabilitation Hospital · CAJohn F. Kennedy Center for the Performing Arts · USKaiser Permanente · USMaineGeneral Medical Center · USNationwide Children's Hospital · USOregon Health & Science University · USPediatrics and Genetics · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
NCATS NIH HHS UL1 TR000445
6 · The paper itself

Abstract

objectiveThis report describes the development of a practice pathway for the identification, evaluation, and management of insomnia in children and adolescents who have autism spectrum disorders (ASDs).

methodsThe Sleep Committee of the Autism Treatment Network (ATN) developed a practice pathway, based on expert consensus, to capture best practices for an overarching approach to insomnia by a general pediatrician, primary care provider, or autism medical specialist, including identification, evaluation, and management. A field test at 4 ATN sites was used to evaluate the pathway. In addition, a systematic literature review and grading of evidence provided data regarding treatments of insomnia in children who have neurodevelopmental disabilities.

resultsThe literature review revealed that current treatments for insomnia in children who have ASD show promise for behavioral/educational interventions and melatonin trials. However, there is a paucity of evidence, supporting the need for additional research. Consensus among the ATN sleep medicine committee experts included: (1) all children who have ASD should be screened for insomnia; (2) screening should be done for potential contributing factors, including other medical problems; (3) the need for therapeutic intervention should be determined; (4) therapeutic interventions should begin with parent education in the use of behavioral approaches as a first-line approach; (5) pharmacologic therapy may be indicated in certain situations; and (6) there should be follow-up after any intervention to evaluate effectiveness and tolerance of the therapy. Field testing of the practice pathway by autism medical specialists allowed for refinement of the practice pathway.

conclusionsThe insomnia practice pathway may help health care providers to identify and manage insomnia symptoms in children and adolescents who have ASD. It may also provide a framework to evaluate the impact of contributing factors on insomnia and to test the effectiveness of nonpharmacologic and pharmacologic treatment strategies for the nighttime symptoms and daytime functioning and quality of life in ASD.

Indexed as

Critical PathwaysAdolescentChildChild Development Disorders, PervasiveDecision TreesGuidelines as TopicHumansSleep Initiation and Maintenance DisordersSurveys and Questionnaires

Identifiers

PMID23118242
PMCPMC9923883
OpenAlexW2118521626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.