ArticleJournal of Korean Neurosurgical Society2012
Atypical metronidazole-induced encephalopathy in anaerobic brain abscess.
Article in Journal of Korean Neurosurgical Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Metronidazole-induced encephalopathy: a systematic review.Journal of neurology · 2020Pooled it
- MRI Findings and Topographic Distribution of Lesions in Metronidazole-Induced Encephalopathy.Cureus · 2022Article
- Asymmetric Magnetic Resonance Imaging Findings in Metronidazole-induced Encephalopathy.Internal medicine (Tokyo, Japan) · 2018Article
- Metronidazole-induced encephalopathy associated with treatment for liver abscesses.Journal of general and family medicine · 2017Article
- Clinical and Neuroradiological Spectrum of Metronidazole Induced Encephalopathy: Our Experience and the Review of Literature.Journal of clinical and diagnostic research : JCDR · 2016Review
- Metronidazole-induced encephalopathy: not always a reversible situation.Neurocritical care · 2015Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metronidazole-induced encephalopathy is a very rare complication of the long standing use of metronidazole. The encephalopathy is bilateral and symmetric in nature. We report on the magnetic resonance imaging (MRI) and clinical course of metronidazole-induced encephalopathy in a 60-year-old female with a persistent anaerobic brain abscess after draining of the abscess. After 3 months of metronidazole administration, the patient complained of dysarthria, tingling sense of all extremities, and left hemiparesis. MRI revealed symmetric hyperintensity lesions in medulla, pons, dentate nuclei of cerebellum, and splenium of corpus callosum, all of which represent typical findings of metronidazole-induced encephalopathy. In addition, asymmetric lesions in midbrain, thalamus, putamen and cerebral subcortical white matter were noted. The patient recovered after discontinuation of metronidazole and the remaining abscess was successfully treated with meropenem and levofloxacine.
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