ArticleFrontiers in immunology2012
Current understanding of the Trypanosoma cruzi-cardiomyocyte interaction.
Article in Frontiers in immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Cafestol and kahweol: coffee diterpenes with trypanocidal activity and cardioprotective effects.Frontiers in cellular and infection microbiology · 2026Article
- Chagas Heart Disease: Beyond a Single Complication, from Asymptomatic Disease to Heart Failure.Journal of clinical medicine · 2022Review
- Modulation of miR-145-5p and miR-146b-5p levels is linked to reduced parasite load in H9C2 Trypanosoma cruzi infected cardiomyoblasts.Scientific reports · 2022Article
- Galectins in Chagas Disease: A Missing Link BetweenFrontiers in microbiology · 2021Review
- Article
- A Combination of Itraconazole and Amiodarone Is Highly Effective againstThe American journal of tropical medicine and hygiene · 2019Article
- Vimentin and Anti Vimentin Antibodies in Chagas' Disease.Arquivos brasileiros de cardiologia · 2018Article
- Article
- Oral Versus Intragastric Inoculation: Similar Pathways ofFrontiers in immunology · 2018Review
- Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruzi.PLoS neglected tropical diseases · 2016Article
- Mir-190b negatively contributes to the Trypanosoma cruzi-infected cell survival by repressing PTEN protein expression.Memorias do Instituto Oswaldo Cruz · 2015Article
- Role of cyclooxygenase-2 in Trypanosoma cruzi survival in the early stages of parasite host-cell interaction.Memorias do Instituto Oswaldo Cruz · 2015Article
- Galectin-1 Prevents Infection and Damage Induced by Trypanosoma cruzi on Cardiac Cells.PLoS neglected tropical diseases · 2015Article
- Inhibition of cyclooxygenase-1 and cyclooxygenase-2 impairs Trypanosoma cruzi entry into cardiac cells and promotes differential modulation of the inflammatory response.Antimicrobial agents and chemotherapy · 2014Article
- Trypanosoma cruzi-Host Cell Interaction.Frontiers in immunology · 2014Article
- Trypanosoma cruzi highjacks TrkC to enter cardiomyocytes and cardiac fibroblasts while exploiting TrkA for cardioprotection against oxidative stress.Cellular microbiology · 2013Article
- Genetic susceptibility to Chagas disease: an overview about the infection and about the association between disease and the immune response genes.BioMed research international · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trypanosoma cruzi, the etiological agent of Chagas disease, exhibits multiple strategies to ensure its establishment and persistence in the host. Although this parasite has the ability to infect different organs, heart impairment is the most frequent clinical manifestation of the disease. Advances in knowledge of T. cruzi-cardiomyocyte interactions have contributed to a better understanding of the biological events involved in the pathogenesis of Chagas disease. This brief review focuses on the current understanding of molecules involved in T. cruzi-cardiomyocyte recognition, the mechanism of invasion, and on the effect of intracellular development of T. cruzi on the structural organization and molecular response of the target cell.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.