ArticleCurrent genomics2012
Quantitative genetics in the genomics era.
Article in Current genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed.
- Evidence of a genomic basis for growth rate variation in a natural kelp population.Scientific reports · 2026Article
- Heat stress effects on the genetics of growth traits in Thai native chickens (Pradu Hang dum).Animal bioscience · 2024Article
- A proximal LAVA method for genome-wide association and prediction of traits with mixed inheritance patterns.BMC bioinformatics · 2021Article
- Average semivariance yields accurate estimates of the fraction of marker-associated genetic variance and heritability in complex trait analyses.PLoS genetics · 2021Article
- Toward Genome-Based Selection in Asian Seabass: What Can We Learn From Other Food Fishes and Farm Animals?Frontiers in genetics · 2021Review
- Muscle transcriptome analysis reveals genes and metabolic pathways related to mineral concentration in Bos indicus.Scientific reports · 2019Article
- Genomic selection on breeding time in a wild bird population.Evolution letters · 2019Article
- Quantitative epigenetics and evolution.Heredity · 2018Review
- Accounting for Genotype-by-Environment Interactions and Residual Genetic Variation in Genomic Selection for Water-Soluble Carbohydrate Concentration in Wheat.G3 (Bethesda, Md.) · 2018Article
- Whole-genome association and genome partitioning revealed variants and explained heritability for total number of teats in a Yorkshire pig population.Asian-Australasian journal of animal sciences · 2018Article
- Using genome wide association studies to identify common QTL regions in three different genetic backgrounds based on Iberian pig breed.PloS one · 2018Article
- Genomic prediction unifies animal and plant breeding programs to form platforms for biological discovery.Nature genetics · 2017Article
- Deciphering the regulation of porcine genes influencing growth, fatness and yield-related traits through genetical genomics.Mammalian genome : official journal of the International Mammalian Genome Society · 2017Article
- Article
- Genomic approaches to selection in outcrossing perennials: focus on essential oil crops.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2015Review
- Using the Animal Model to Accelerate Response to Selection in a Self-Pollinating Crop.G3 (Bethesda, Md.) · 2015Article
- Using genomics to characterize evolutionary potential for conservation of wild populations.Evolutionary applications · 2014Article
- Quantitative genetics in the study of virus-induced disease.Advances in virus research · 2014Review
- Article
- Pedigree-free estimates of heritability in the wild: promising prospects for selfing populations.PloS one · 2013Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genetic analysis of quantitative or complex traits has been based mainly on statistical quantities such as genetic variances and heritability. These analyses continue to be developed, for example in studies of natural populations. Genomic methods are having an impact on progress and prospects. Actual relationships of individuals can be estimated enabling novel quantitative analyses. Increasing precision of linkage mapping is feasible with dense marker panels and designed stocks allowing multiple generations of recombination, and large SNP panels enable the use of genome wide association analysis utilising historical recombination. Whilst such analyses are identifying many loci for disease genes and traits such as height, typically each individually contributes a small amount of the variation. Only by fitting all SNPs without regard to significance can a high proportion be accounted for, so a classical polygenic model with near infinitesimally small effects remains a useful one. Theory indicates that a high proportion of variants will have low minor allele frequency, making detection difficult. Genomic selection, based on simultaneously fitting very dense markers and incorporating these with phenotypic data in breeding value prediction is revolutionising breeding programmes in agriculture and has a major potential role in human disease prediction.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.