Evidence map›Paper›PMID 23115347›Full record

ArticlePsychosomatic medicine

Grapheme-color synesthesia and posttraumatic stress disorder: preliminary results from the veterans health study.

Stuart N Hoffman, Xiaopeng Zhang, Porat M Erlich, Joseph A Boscarino

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Psychosomatic medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Language evolution: examining the link between cross-modality and aggression through the lens of disorders.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Article
  3. Synaesthesia: a distinct entity that is an emergent feature of adaptive neurocognitive differences.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Stuart N HoffmanDepartment of Neurology, Geisinger Clinic, Danville, PA 17822-4400, USA.
Xiaopeng Zhang
Porat M Erlich
Joseph A Boscarino
Geisinger Medical Center · US

Funding

Mental Health Services in NY after WTC DisasterR01MH066403 · NIMH · NEW YORK ACADEMY OF MEDICINE · PI BOSCARINO, JOSEPH A · 2002 to 2004
$1.6M
Developing PTSD Risk Assessment Tools Using the World Trade Center Outcome StudyR21MH086317 · NIMH · GEISINGER CLINIC · PI BOSCARINO, JOSEPH A · 2009 to 2010
$437k
NIMH NIH HHS R01 MH066403NIMH NIH HHS R21 MH086317NIMH NIH HHS R21-MH-086317
6 · The paper itself

Abstract

objectivePosttraumatic stress disorder (PTSD) is associated with altered neuropsychological function, possibly including complex visual information processing. Grapheme-color synesthesia refers to the phenomenon that a particular letter or number elicits the visual perception of a specific color. The study objective was to assess if grapheme-color synesthesia was associated with PTSD among US veterans.

methodWe surveyed 700 veterans who were outpatients in a multihospital system in Pennsylvania. All veterans had served at least one warzone deployment. PTSD and grapheme-color synesthesia were assessed using validated research instruments.

resultsThe mean age of veterans was 59 years, and 96% were men. The prevalence of current PTSD was 7% (95% confidence interval [CI] = 5.1-8.8), and current partial PTSD was 11% (95% CI = 9.3-14.0). The prevalence of current depression was 6% (95% CI = 4.7-8.3). Altogether, 6% (95% CI = 4.8-8.5) of veterans screened positive for grapheme-color synesthesia. Bivariate analyses suggested that grapheme-color synesthesia was associated with current PTSD (odds ratio [OR] = 3.4, p = .004) and current partial PTSD (OR = 2.4, p = .013), but not current depression (OR = 1.1, p = .91). Multivariate logistic regression results, adjusting for age, sex, marital status, level of education, current psychotropic medication use, and concussion history, confirmed these results.

conclusionsGrapheme-color synesthesia seems to be associated with PTSD among veterans who had been deployed. This finding may have implications for PTSD diagnostic screening and treatment. Research is recommended to confirm this finding and to determine if synesthesia is a risk indicator for PTSD among nonveterans.

Indexed as

AssociationColor PerceptionPattern Recognition, VisualSemanticsVeteransComorbidityFemaleHumansMajor Depressive DisorderMaleMass ScreeningMiddle AgedRisk FactorsStress Disorders, Post-Traumatic

Identifiers

PMID23115347
PMCPMC3556719
OpenAlexW2049877669

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.