ArticleAntimicrobial agents and chemotherapy2013
Clonal structure, extended-spectrum β-lactamases, and acquired AmpC-type cephalosporinases of Escherichia coli populations colonizing patients in rehabilitation centers in four countries.
Article in Antimicrobial agents and chemotherapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Epidemic potential of Escherichia coli ST131 and Klebsiella pneumoniae ST258: a systematic review and meta-analysis.BMJ open · 2016Pooled it
- Genomic Characterization of a Class 2/1 Hybrid Integron-Driven Multidrug-ResistantVeterinary sciences · 2025Article
- In Silico Detection of Virulence Genes in Whole-Genome Sequences of Extra-Intestinal PathogenicCurrent issues in molecular biology · 2025Article
- ESBL- and pAmpC-producing Enterobacterales from Swedish dogs and cats 2017-2021: a retrospective study.Acta veterinaria Scandinavica · 2025Article
- Detecting Class 1 Integrons and Their Variable Regions inAntibiotics (Basel, Switzerland) · 2024Article
- High risk of intestinal colonization with ESBL-producing Escherichia coli among soldiers of military contingents in specific geographic regions.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023Article
- Genomic and Temporal Trends in Canine ExPEC Reflect Those of Human ExPEC.Microbiology spectrum · 2022Article
- Genomic Analysis of ESBL-ProducingAntibiotics (Basel, Switzerland) · 2022Article
- Epidemiologic and molecular characterization of β-lactamase-producing multidrug-resistant uropathogenic Escherichia coli isolated from asymptomatic hospitalized patients.International microbiology : the official journal of the Spanish Society for Microbiology · 2022Article
- High prevalence of blaScientific reports · 2021Article
- Temporal Trend of ST131 Clone among UrinaryMicroorganisms · 2021Article
- Citrobacter telavivum sp. nov. with chromosomal mcr-9 from hospitalized patients.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- Molecular Characteristics of Extraintestinal PathogenicMicroorganisms · 2020Article
- High Prevalence of ST131 Subclades C2-Frontiers in cellular and infection microbiology · 2020Article
- Pathogenic Factors Correlate With Antimicrobial Resistance Among ClinicalFrontiers in microbiology · 2020Article
- Article
- Understanding the Epidemiology of Multi-Drug Resistant Gram-Negative Bacilli in the Middle East Using a One Health Approach.Frontiers in microbiology · 2019Review
- The Transmissibility of Antibiotic-Resistant Enterobacteriaceae in Intensive Care Units.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Molecular Characterization of Escherichia coli Strains Isolated from Retail Meat That Harbor blaCTX-M and fosA3 Genes.Antimicrobial agents and chemotherapy · 2016Article
- High prevalence of Salmonella and IMP-4-producing Enterobacteriaceae in the silver gull on Five Islands, Australia.The Journal of antimicrobial chemotherapy · 2016Article
Corrections and comments
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Authors and funding
21 authors at 9 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prospective project MOSAR was conducted in five rehabilitation units: the Berck Maritime Hôpital (Berck, France), Fondazione Santa Lucia (Rome, Italy), Guttmann Institute (GI; Barcelona, Spain), and Loewenstein Hospital and Tel-Aviv Souraski Medical Center (TA) (Tel-Aviv, Israel). Patients were screened for carriage of Enterobacteriaceae resistant to expanded-spectrum cephalosporins (ESCs) from admission until discharge. The aim of this study was to characterize the clonal structure, extended-spectrum β-lactamases (ESBLs), and acquired AmpC-like cephalosporinases in the Escherichia coli populations collected. A total of 376 isolates were randomly selected. The overall number of sequence types (STs) was 76, including 7 STs that grouped at least 10 isolates from at least three centers each, namely, STs 10, 38, 69, 131, 405, 410, and 648. These clones comprised 65.2% of all isolates, and ST131 alone comprised 41.2%. Of 54 STs observed only in one center, some STs played a locally significant role, like ST156 and ST393 in GI or ST372 and ST398 in TA. Among 16 new STs, five arose from evolution within the ST10 and ST131 clonal complexes. ESBLs and AmpCs accounted for 94.7% and 5.6% of the ESC-hydrolyzing β-lactamases, respectively, being dominated by the CTX-M-like enzymes (79.9%), followed by the SHV (13.5%) and CMY-2 (5.3%) types. CTX-M-15 was the most prevalent β-lactamase overall (40.6%); other ubiquitous enzymes were CTX-M-14 and CMY-2. Almost none of the common clones correlated strictly with one β-lactamase; although 58.7% of ST131 isolates produced CTX-M-15, the clone also expressed nine other enzymes. A number of clone variants with specific pulsed-field gel electrophoresis and ESBL types were spread in some locales, potentially representing newly emerging E. coli epidemic strains.
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