Evidence map›Paper›PMID 23114752›Full record

ArticleAntimicrobial agents and chemotherapy2013

Interaction of platelets and anidulafungin against Aspergillus fumigatus.

Susanne Perkhofer, Barbara Striessnig, Bettina Sartori, Barbara Hausott, Helmut W Ott, Cornelia Lass-Flörl

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Antifungal Innate Immunity.Advances in experimental medicine and biology · 2025
    Review
  2. Article
  3. Dysregulation of Key Proteinases inReports of biochemistry & molecular biology · 2021
    Article
  4. Article
  5. Review
  6. Differential gene expression in Aspergillus fumigatus induced by human platelets in vitro.International journal of medical microbiology : IJMM · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Susanne PerkhoferUniversity of Applied Sciences Tyrol, Innsbruck, Austria. Susanne.Perkhofer@fhg-tirol.ac.at
Barbara Striessnig
Bettina Sartori
Barbara Hausott
Helmut W Ott
Cornelia Lass-Flörl
Innsbruck Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The combination of platelets and anidulafungin at 0.03 μg/ml significantly (P < 0.05) reduced the germination rate and hyphal elongation in Aspergillus fumigatus compared to those with either anidulafungin only or an untreated control. Platelets decreased the expression of the fks gene, which plays an important role in cell wall synthesis. Our results suggest that human platelets plus anidulafungin might contribute to defense against A. fumigatus.

Indexed as

AnidulafunginAntifungal AgentsAspergillus fumigatusBlood PlateletsCell Culture TechniquesEchinocandinsFungal ProteinsGene ExpressionGlucosyltransferasesHumansHyphaeInvasive Pulmonary AspergillosisMicrobial Sensitivity TestsAnidulafunginAntifungal AgentsEchinocandinsFungal ProteinsGlucosyltransferases

Identifiers

PMID23114752
PMCPMC3535898
OpenAlexW2127279229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.