Evidence map›Paper›PMID 23114712›Full record

ArticleCancer biology & therapy2013

Adult primary pulmonary primitive neuroectodermal tumor: molecular features and translational opportunities.

Mirela Andrei, Stewart F Cramer, Zachary B Kramer, Amer Zeidan, Bishoy Faltas

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Cancer biology & therapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A rare radiotherapy-sensitive primitive neuroectodermal tumor withThe Journal of international medical research · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Primary pulmonary Ewing sarcoma/peripheral primitive neuroectodermal tumor.Proceedings (Baylor University. Medical Center) · 2020
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Primary ewings sarcoma of the lung.Journal of clinical and diagnostic research : JCDR · 2015
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Mirela AndreiDepartment of Internal Medicine, Rochester General Hospital, Rochester, NY USA. mirela.andrei@rochestergeneral.org
Stewart F Cramer
Zachary B Kramer
Amer Zeidan
Bishoy Faltas
Rochester General Hospital · USCornell University · USSidney Kimmel Comprehensive Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primitive neuroectodermal tumors (PNET) arising directly from the lung are very rare but particularly aggressive neoplasms. We report a case of a 31-y-old man with primary pulmonary neuroectodermal tumor. We review the clinical as well as pathological features. As typical for these tumors, the diagnosis was initially delayed in our patient and prognosis was poor despite aggressive surgical resection, postoperative chemotherapy and local irradiation. Recent biological insights have revealed unique chromosomal translocations crucial to the pathogenesis of these tumors, most notably the EWS-FLI-1 translocation. We provide an overview of the molecular features of the Ewing Sarcoma Family of Tumors (ESFT) including PNET and their potential implications for therapeutic targeting.

Indexed as

AdultBiopsyHumansLungLung NeoplasmsMaleNeuroectodermal Tumors, Primitive, PeripheralOncogene Proteins, FusionProto-Oncogene Protein c-fli-1RadiographyRNA-Binding Protein EWSEWS-FLI fusion proteinOncogene Proteins, FusionProto-Oncogene Protein c-fli-1RNA-Binding Protein EWSadultEwing sarcomalungprimitive neuroectodermal tumor

Identifiers

PMID23114712
PMCPMC3572002
OpenAlexW1967039205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.