Evidence map›Paper›PMID 23114604›Full record

ReviewThe Journal of clinical investigation2012

Perspectives on whole-organ assembly: moving toward transplantation on demand.

Alejandro Soto-Gutierrez, Jason A Wertheim, Harald C Ott, Thomas W Gilbert

Abstract readReview
In one paragraph

Review in The Journal of clinical investigation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Review
  2. Exploring Insulin Production Following Alveolar Islet Transplantation (AIT).International journal of molecular sciences · 2021
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Novel technology for liver regeneration and replacement.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2016
    Article
  11. Article
  12. Article
  13. Liver-Regenerative Transplantation: Regrow and Reset.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2016
    Review
  14. Article
  15. Article
  16. Challenging Regeneration to Transform Medicine.Stem cells translational medicine · 2016
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alejandro Soto-GutierrezDepartment of Pathology, Transplantation Section of Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA. sotogutierreza@upmc.edu
Jason A Wertheim
Harald C Ott
Thomas W Gilbert

Funding

Engineering of hepatic grafts with decellularized native matricesR00DK083556 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SOTO-GUTIERREZ, ALEJANDRO · 2011 to 2013
$707k
Tissue Specific ECM Scaffold for the Functional Repair of the Vocal Fold Lamina PR03DC009655 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GILBERT, THOMAS W. · 2009 to 2011
$360k
Engineering of hepatic grafts with decellularized native matricesK99DK083556 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SOTO-GUTIERREZ, ALEJANDRO · 2009 to 2010
$180k
Cardiac Remodeling with Organ Specific Extracellular Matrix ScaffoldsR03EB009237 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GILBERT, THOMAS W. · 2009 to 2010
$145k
NIBIB NIH HHS EB009237NIBIB NIH HHS R03 EB009237NIDCD NIH HHS DC009655NIDCD NIH HHS R03 DC009655NIDDK NIH HHS DK083556NIDDK NIH HHS K99 DK083556NIDDK NIH HHS R00 DK083556PHS HHS 234-2005-37011C
6 · The paper itself

Abstract

There is an ever-growing demand for transplantable organs to replace acute and chronically damaged tissues. This demand cannot be met by the currently available donor organs. Efforts to provide an alternative source have led to the development of organ engineering, a discipline that combines cell biology, tissue engineering, and cell/organ transplantation. Over the last several years, engineered organs have been implanted into rodent recipients and have shown modest function. In this article, we summarize the most recent advances in this field and provide a perspective on the challenges of translating this promising new technology into a proven regenerative therapy.

Indexed as

Organ TransplantationAnimalsHumansMiceRatsRegenerative MedicineTissue Engineering

Identifiers

PMID23114604
PMCPMC3484436

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.