ArticleMultidisciplinary respiratory medicine2012
Prominent features of platelet count, plateletcrit, mean platelet volume and platelet distribution width in pulmonary tuberculosis.
Article in Multidisciplinary respiratory medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.
- Effect of HIIT on hemostasis and vascular stiffness: a systematic review and meta-analysis of randomized controlled trials.Frontiers in cardiovascular medicine · 2025Pooled it
- Immunological correlates of mycobacterial growth inhibition describe a spectrum of tuberculosis infection.Scientific reports · 2018Trial
- Association of Altered Baseline Hematological Parameters with Adverse Tuberculosis Treatment Outcomes.Pathogens (Basel, Switzerland) · 2025Article
- Platelet-based biomarkers: A new frontier in inflammation monitoring for respiratory infections.F1000Research · 2025Article
- Inflammation indices in association with periodontitis and cancer.Periodontology 2000 · 2024Review
- Causal relationship between physical activity and platelet traits: a Mendelian randomization study.Frontiers in physiology · 2024Article
- Evaluation of platelet indices as markers of tuberculosis among children in India.ERJ open research · 2024Article
- Mimicking platelet indices in patients with malaria and dengue hemorrhagic fever: characteristics and clinical applications.Tropical medicine and health · 2022Article
- Use of Platelet Parameters in the Differential Diagnosis of Lung Adenocarcinoma-Associated Malignant Pleural Effusion and Tuberculous Pleural Effusion.Disease markers · 2022Article
- Association between depression or anxiety symptoms and immune-inflammatory characteristics in in-patients with tuberculosis: A cross-sectional study.Frontiers in psychiatry · 2022Article
- Immunologic biomarkers, morbidity and mortality among HIV patients hospitalised in a Tertiary Care Hospital in the Brazilian Amazon.BMC infectious diseases · 2021Article
- Tuberculosis seroprevalence and comparison of hematology and biochemistry parameters between seropositive and seronegative captive Asian elephants of Nepal.The Journal of veterinary medical science · 2021Article
- Mean platelet volume (MPV): new diagnostic indices for co-morbidity of tuberculosis and diabetes mellitus.BMC infectious diseases · 2021Article
- Platelet Activation and the Immune Response to Tuberculosis.Frontiers in immunology · 2021Review
- Article
- A valuable computed tomography-based new diagnostic tool for severe chest lesions in active pulmonary tuberculosis: combined application of influencing factors.Scientific reports · 2020Article
- Increased levels of reactive oxygen species in platelets and platelet-derived microparticles and the risk of respiratory failure in HIV/AIDS patients.Memorias do Instituto Oswaldo Cruz · 2020Article
- A routine blood test-associated predictive model and application for tuberculosis diagnosis: a retrospective cohort study from northwest China.The Journal of international medical research · 2019Article
- Branch retinal vein occlusion associated with platelet activationTurkish journal of medical sciences · 2019Article
- Could Platelet Indices and Neutrophil to Lymphocyte Ratio Be New Biomarkers for Differentiation of Arteritic Anterior Ischemic Neuropathy from Non-Arteritic Type?Neuro-ophthalmology (Aeolus Press) · 2018Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelled
backgroundWe aimed to investigate the relation of platelet count (PLT) and plateletcrit (PCT), mean platelet volume (MPV) and platelet distribution width (PDW) with other acute phase reactants and radiological extent in pulmonary tuberculosis (PTB).
methodsOne hundred patients with PTB (Group 1), 50 patients with community-acquired pneumonia (Group 2) and 28 healthy control individuals (Group 3) were included in this analytic study.
resultsWBC (White Blood Cell), ESR (Eritrocyte Sedimentation Rate), CRP (C-Reactive Protein), PLT and PCT values were both in Group 1 and Group 2 than in Group 3. PDW values were significantly higher in Group 1 than Group 3. WBC, ESR and CRP values were lower, while PLT and PCT values were higher in the Group 1 compared to Group 2 (p < 0.001). PLT was positively correlated with CRP and ESR values in the tuberculosis group (p < 0.001), while it was not correlated with CRP and ESR in the pneumonia group (p > 0.05). ESR, CRP, PLT and PCT values were found higher in radiological advanced stage (Stage 3) patients with PTB, while hemoglobin (Hb) was found lower (p < 0.05). Higher WBC, ESR, CRP and PCT values as well as radiological advanced stage were more common in PTB patients with thrombocytosis compared to the patients with normal platelet count, whereas Hb was found lower in these patients.
conclusionsThis study indicates that reactive thrombocytosis and higher PCT and PDW develop frequently in PTB and there is a relation between thrombocytosis and acute phase reactants, that is the inflammatory response. In addition, tuberculosis with radiological advanced stage is seen more frequently in the patients with thrombocytosis and higher PCT, drawing attention to the possible role of platelets in the cell-based immune process of tuberculosis.
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Registered trials
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