ArticleJournal of neurophysiology2013
Short-term synaptic depression and stochastic vesicle dynamics reduce and shape neuronal correlations.
Article in Journal of neurophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Interactions across hemispheres in prefrontal cortex reflect global cognitive processing.Nature communications · 2026Article
- Inferring synaptic transmission from the stochastic dynamics of the quantal content: An analytical approach.PLoS computational biology · 2025Article
- Article
- Task-evoked activity quenches neural correlations and variability across cortical areas.PLoS computational biology · 2020Article
- A theoretical framework for analyzing coupled neuronal networks: Application to the olfactory system.PLoS computational biology · 2017Article
- Phase changes in neuronal postsynaptic spiking due to short term plasticity.PLoS computational biology · 2017Article
- Downstream Effect of Ramping Neuronal Activity through Synapses with Short-Term Plasticity.Neural computation · 2016Article
- The mechanics of state-dependent neural correlations.Nature neuroscience · 2016Review
- Article
- Poisson-like spiking in circuits with probabilistic synapses.PLoS computational biology · 2014Article
- Axonal and synaptic failure suppress the transfer of firing rate oscillations, synchrony and information during high frequency deep brain stimulation.Neurobiology of disease · 2014Article
- The correlation structure of local neuronal networks intrinsically results from recurrent dynamics.PLoS computational biology · 2014Article
- Theoretical models of synaptic short term plasticity.Frontiers in computational neuroscience · 2013Article
- Mathematical analysis and algorithms for efficiently and accurately implementing stochastic simulations of short-term synaptic depression and facilitation.Frontiers in computational neuroscience · 2013Article
Corrections and comments
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3 authors.
Funding
Abstract
Correlated neuronal activity is an important feature in many neural codes, a neural correlate of a variety of cognitive states, as well as a signature of several disease states in the nervous system. The cellular and circuit mechanics of neural correlations is a vibrant area of research. Synapses throughout the cortex exhibit a form of short-term depression where increased presynaptic firing rates deplete neurotransmitter vesicles, which transiently reduces synaptic efficacy. The release and recovery of these vesicles are inherently stochastic, and this stochasticity introduces variability into the conductance elicited by depressing synapses. The impact of spiking and subthreshold membrane dynamics on the transfer of neuronal correlations has been studied intensively, but an investigation of the impact of short-term synaptic depression and stochastic vesicle dynamics on correlation transfer is lacking. We find that short-term synaptic depression and stochastic vesicle dynamics can substantially reduce correlations, shape the timescale over which these correlations occur, and alter the dependence of spiking correlations on firing rate. Our results show that short-term depression and stochastic vesicle dynamics need to be taken into account when modeling correlations in neuronal populations.
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