ArticlePublic health nutrition2013
Modelling fortification of corn masa flour with folic acid and the potential impact on Mexican-American women with lower acculturation.
Article in Public health nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Pooled it
- Digital tools and technologies used in food fortification: A scoping review.Annals of the New York Academy of Sciences · 2025Article
- Multivitamin Use Among Hispanic Women of Reproductive Age in the United States, 2013-2022.Journal of women's health (2002) · 2024Article
- Update on the impact of voluntary folic acid fortification of corn masa flour on red blood cell folate concentrations-National Health and Nutrition Examination Survey, 2011-March 2020.Birth defects research · 2024Article
- Spina bifida folate fortification in Brazil, update 2022: a cross-sectional study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Barriers and facilitators to the implementation of mandatory folate fortification as an evidence-based policy to prevent neural tube defects.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Review
- Impact of Voluntary Folic Acid Fortification of Corn Masa Flour on RBC Folate Concentrations in the U.S. (NHANES 2011-2018).Nutrients · 2021Article
- Adding folic acid to corn Masa flour: Partnering to improve pregnancy outcomes and reduce health disparities.Preventive medicine · 2018Review
- Finding the genetic mechanisms of folate deficiency and neural tube defects-Leaving no stone unturned.American journal of medical genetics. Part A · 2017Review
- Air pollution, neighborhood acculturation factors, and neural tube defects among Hispanic women in California.Birth defects research · 2017Article
- Retrospective Assessment of Cost Savings From Prevention: Folic Acid Fortification and Spina Bifida in the U.S.American journal of preventive medicine · 2016Article
- Blood folate concentrations among women of childbearing age by race/ethnicity and acculturation, NHANES 2001-2010.Maternal & child nutrition · 2016Article
- The National Spina Bifida Patient Registry: profile of a large cohort of participants from the first 10 clinics.The Journal of pediatrics · 2015Article
- Fortification of corn masa flour with folic acid in the United States: an overview of the evidence.Annals of the New York Academy of Sciences · 2014Review
- Estimate of the potential impact of folic acid fortification of corn masa flour on the prevention of neural tube defects.Birth defects research. Part A, Clinical and molecular teratology · 2013Article
- Public health science agenda for congenital heart defects: report from a Centers for Disease Control and Prevention experts meeting.Journal of the American Heart Association · 2013Article
- Modeling fortification of corn masa flour with folic acid: the potential impact on exceeding the tolerable upper intake level for folic acid, NHANES 2001-2008.Food & nutrition research · 2013Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveHispanics with lower acculturation may be at higher risk for neural tube defects compared with those with higher acculturation due to lower total folic acid intake or other undetermined factors. Modelling has indicated that fortification of corn masa flour with folic acid could selectively target Mexican Americans more than other race/ethnicities. We assessed whether fortification of corn masa flour with folic acid could selectively increase folic acid intake among Mexican-American women with lower acculturation, as indicated by specific factors (language preference, country of origin, time living in the USA).
designWe used dietary intake and dietary supplement data from the National Health and Nutrition Examination Survey 2001-2008, to estimate the amount of additional total folic acid that could be consumed if products considered to contain corn masa flour were fortified at 140 μg of folic acid per 100 g of corn masa flour.
settingUSA. SUBJECTS: Non-pregnant women aged 15-44 years (n 5369).
resultsMexican-American women who reported speaking Spanish had a relative percentage change in usual daily total folic acid intake of 30·5 (95 % CI 27·8, 33·4) %, compared with 8·3 (95 % CI 7·3, 9·4) % for Mexican-American women who reported speaking English. We observed similar results for other acculturation factors. An increase of 6·0 percentage points in the number of Mexican-American women who would achieve the recommended intake of ≥400 μg folic acid/d occurred with fortification of corn masa flour; compared with increases of 1·1 percentage points for non-Hispanic whites and 1·3 percentage points for non-Hispanic blacks. An even greater percentage point increase was observed among Mexican-American women who reported speaking Spanish (8·2).
conclusionsFortification of corn masa flour could selectively increase total folic acid intake among Mexican-American women, especially targeting Mexican-American women with lower acculturation, and result in a decrease in the number of pregnancies affected by neural tube defects.
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