ArticlePopulation health metrics2012
Systematic review of general burden of disease studies using disability-adjusted life years.
Article in Population health metrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.
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Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A systematic review of studies that estimated the burden of chronic non-communicable rare diseases using disability-adjusted life years.Orphanet journal of rare diseases · 2024Pooled it
- Burden of infectious disease studies in Europe and the United Kingdom: a review of methodological design choices.Epidemiology and infection · 2023Pooled it
- Estimating the burden of foodborne diseases in Japan.Bulletin of the World Health Organization · 2015Pooled it
- Pre-pandemic sub-national disparities in the disease burden of ischemic heart disease and stroke in France.BMC cardiovascular disorders · 2026Article
- How eight health risks and chronic conditions relate: identifying associations and profiling characteristics of multiple health risk factors among 14 disease groups and 30 common chronic conditions in Denmark.Scandinavian journal of public health · 2026Article
- Catalogue of eight psychological and behavioural health risks and related disparities among 199 chronic conditions in Denmark.Scandinavian journal of public health · 2026Article
- Sub-national disparities in disease burden of diabetes mellitus and chronic kidney disease in France: a pre-pandemic analysis.Archives of public health = Archives belges de sante publique · 2025Article
- Provenance and Funding of Extremely Cited Biomedical Articles Published Between 2003 and 2024.JAMA health forum · 2025Article
- Healthcare and productivity loss costs in young adults after bacterial meningitis: a cross-sectional follow-up study.BMJ paediatrics open · 2025Article
- Burden of Substance Use Disorders in the Middle East and North Africa from 1990 to 2019.Balkan medical journal · 2025Article
- Deriving disability weights for the Netherlands: findings from the Dutch disability weights measurement study.Population health metrics · 2024Article
- Human resources for health and maternal mortality in Latin America and the Caribbean over the last three decades: a systemic-perspective reflections.International journal for equity in health · 2024Article
- Burden of disease attributable to risk factors in European countries: a scoping literature review.Archives of public health = Archives belges de sante publique · 2023Article
- Assessing Variation in the Individual-Level Impacts of a Multihost Pathogen.Transboundary and emerging diseases · 2023Article
- A scoping review of burden of disease studies estimating disability-adjusted life years due to Taenia solium.PLoS neglected tropical diseases · 2022Article
- Catalogue of socioeconomic disparities and characteristics of 199+ chronic conditions-A nationwide register-based population study.PloS one · 2022Article
- Article
- Regional and state-level patterns of type 2 diabetes prevalence in Mexico over the last three decades.Diabetes research and clinical practice · 2021Article
- Socioeconomic Burden of Bloodstream Infections Caused by Carbapenem-ResistantInfection and drug resistance · 2021Article
- Global Burden of Ischemic Heart Disease and Attributable Risk Factors, 1990-2017: A Secondary Analysis Based on the Global Burden of Disease Study 2017.Clinical epidemiology · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelled
objectiveTo systematically review the methodology of general burden of disease studies. Three key questions were addressed: 1) what was the quality of the data, 2) which methodological choices were made to calculate disability adjusted life years (DALYs), and 3) were uncertainty and risk factor analyses performed? Furthermore, DALY outcomes of the included studies were compared.
methodsBurden of disease studies (1990 to 2011) in international peer-reviewed journals and in grey literature were identified with main inclusion criteria being multiple-cause studies that quantified the burden of disease as the sum of the burden of all distinct diseases expressed in DALYs. Electronic database searches included Medline (PubMed), EMBASE, and Web of Science. Studies were collated by study population, design, methods used to measure mortality and morbidity, risk factor analyses, and evaluation of results.
resultsThirty-one studies met the inclusion criteria of our review. Overall, studies followed the Global Burden of Disease (GBD) approach. However, considerable variation existed in disability weights, discounting, age-weighting, and adjustments for uncertainty. Few studies reported whether mortality data were corrected for missing data or underreporting. Comparison with the GBD DALY outcomes by country revealed that for some studies DALY estimates were of similar magnitude; others reported DALY estimates that were two times higher or lower.
conclusionsOvercoming "error" variation due to the use of different methodologies and low-quality data is a critical priority for advancing burden of disease studies. This can enlarge the detection of true variation in DALY outcomes between populations or over time.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.