Evidence map›Paper›PMID 23113829›Full record

ArticleDrug and alcohol review2013

Increased hepatitis C virus vaccine clinical trial literacy following a brief intervention among people who inject drugs.

Bethany White, Annie Madden, Margaret Hellard, Thomas Kerr, Maria Prins, Kimberly Page, Gregory J Dore, Lisa Maher

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol review, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Health Literacy Studies Conducted in Australia: A Scoping Review.International journal of environmental research and public health · 2019
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 4 countries.

Bethany WhiteViral Hepatitis Epidemiology and Prevention Program, The Kirby Institute, University of New South Wales, Sydney, Australia.
Annie Madden
Margaret Hellard
Thomas Kerr
Maria Prins
Kimberly Page
Gregory J Dore
Lisa Maher
Australian Centre for HIV and Hepatitis Virology Research · AUAIDS Vancouver · CAAlcohol and Drug Foundation · AUBurnet Institute · AUGGD Amsterdam · NLUniversity of California, San Francisco · USUNSW Sydney · AU

Funding

Acute Hepatitis C Infection in Young InjectorsR01DA016017 · NIDA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI PAGE, KIMBERLY · 2002 to 2018
$14.0M
Translational CoreU19AI040034 · NIAID · STANFORD UNIVERSITY · PI WRIGHT, TERESA L. · 1996 to 2009
$8.1M
NIAID NIH HHS 5 U19 AI40034-13NIAID NIH HHS U19 AI040034NIDA NIH HHS 2 R01 DA016017-03A1NIDA NIH HHS R01 DA016017
6 · The paper itself

Abstract

INTRODUCTION AND

aimsWhile people who inject drugs are at high risk of hepatitis C virus (HCV) infection and will be the target population for future HCV vaccine trials, little is known about clinical trial literacy (CTL) in this group. We assessed the impact of a brief intervention (BI) designed to improve HCV vaccine CTL among people who inject drugs in Sydney, Australia. DESIGN AND

methodsPeople who inject drugs enrolled in a community-based prospective observational study between November 2008 and September 2010 (n = 102) completed a CTL assessment followed immediately by the BI. Post-test assessment was conducted at 24 weeks.

resultsThe median age of the sample was 27 years, 73% were male and 60% had 10 or less years of schooling. The median time since first injection was 5 years and 20% reported daily or more frequent injecting. The mean number of correct responses increased from 5.3 to 6.3/10 (t = -4.2; 101df, P < 0.001) 24 weeks post-intervention. Statistically significant differences were observed for three knowledge items with higher proportions of participants correctly answering questions related to randomisation (P = 0.002), blinding (P = 0.005) and vaccine-induced seropositivity (P = 0.003) post-intervention. DISCUSSION AND

conclusionsA significant increase in HCV vaccine CTL was observed, suggesting that new and relatively novel concepts can be learned and recalled in this group. These findings support the feasibility of future trials among this population. [Correction added on 21 November 2012, after first online publication: T-score for mean number of correct responses was corrected to '-4.2' in the Results section.]

Indexed as

Health LiteracyPatient Education as TopicViral Hepatitis VaccinesAdultAustraliaFemaleHepatitis CHumansMaleProspective StudiesSubstance Abuse, IntravenousViral Hepatitis Vaccinesbrief interventionclinical trial literacyhepatitis C virusinjecting drug usevaccine preparedness study

Identifiers

PMID23113829
PMCPMC3567229
OpenAlexW1538364887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.