Evidence map›Paper›PMID 23113809›Full record

ArticleJournal of clinical and experimental neuropsychology2013

Development of normative neuropsychological performance in Thailand for the assessment of HIV-associated neurocognitive disorders.

Jodi Heaps, Victor Valcour, Thep Chalermchai, Robert Paul, Somprartthana Rattanamanee, Umaporn Siangphoe, Pasiri Sithinamsuwan, Parnsiri Chairangsaris, Samart Nidhinandana, Somporn Tipsuk and 4 more

Abstract read
In one paragraph

Article in Journal of clinical and experimental neuropsychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Regression-based Norms for a Neuropsychological Screening Battery in the Filipino Population.Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology · 2026
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  15. Neurocognitive Complications of HIV Infection in Low-Income Countries.Current topics in behavioral neurosciences · 2021
    Article
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jodi HeapsDepartment of Psychology and Behavioral Neuroscience, University of Missouri, St. Louis, MO 63121, USA. jodimheaps@umsl.edu
Victor Valcour
Thep Chalermchai
Robert Paul
Somprartthana Rattanamanee
Umaporn Siangphoe
Pasiri Sithinamsuwan
Parnsiri Chairangsaris
Samart Nidhinandana
Somporn Tipsuk
Duanghathai Suttichom
James Fletcher
Cecilia Shikuma
Jintanat Ananworanich

Funding

University of Hawaii NeuroAIDS SNRPU54NS043049 · NINDS · UNIVERSITY OF HAWAII AT MANOA · PI SHIKUMA, CECILIA M · 2001 to 2005
$7.0M
Peripheral Reservoir of HIV DNA in Monocytes Pivotal to Cognition in HIVR01NS061696 · NINDS · UNIVERSITY OF HAWAII AT MANOA · PI VALCOUR, VICTOR · 2008 to 2012
$3.2M
NINDS NIH HHS R01 NS061696NINDS NIH HHS U54 NS043049
6 · The paper itself

Abstract

International studies of HIV-associated neurocognitive disorder (HAND) are needed to determine the viral and host factors associated with cognitive impairment particularly as more than 80% of HIV+ subjects reside in resource-limited settings. Recent diagnostic nomenclature of HAND requires comparison of cognitive performance specifically to local normative data. To evaluate this need for local norms, we compared normative data obtained locally in Thailand to Western norms. The current study examined cognitive performance in 477 seronegative Thai participants (male = 211, female = 266) who completed a battery of tests sensitive to cognitive changes in HIV. The cohort was divided into three age brackets (20-34; 35-49; 50-65 years) and four educational levels (no education or primary education, less than secondary certificate, high-school/associates degree, bachelor's degree or greater). The Thai cohort was compared (using analysis of covariance, ANCOVA) on a number of measures to a seronegative US cohort (n = 236; male = 198, female = 38) to examine cultural differences in performance. Normative data are provided with age and education stratification. The Thai and US groups performed significantly differently on all neuropsychological measures with the exception of verbal fluency. The Thai group performed better on measures of verbal learning (p < .001) and memory (p < .001) and measures of psychomotor speed (p < .001). Education was a more powerful predictor of performance in the Thai cohort than in the US group. These results highlight the continued need for the development of normative data within local populations. The use of Western norms as a comparison group could lead to inaccurate identification of HAND in culturally distinct groups.

Indexed as

AdultAgedAgingAIDS Dementia ComplexAnalysis of VarianceCognition DisordersCohort StudiesCross-Cultural ComparisonEducational StatusFemaleHawaiiHumansMaleMemoryMiddle AgedNeuropsychological Tests

Identifiers

PMID23113809
PMCPMC3682786

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.