ArticleIranian journal of public health2010
Prevalence of Genes Encoding Bi-Component Leukocidins among Clinical Isolates of Methicillin Resistant Staphylococcus aureus.
Article in Iranian journal of public health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05828550 (Detection of Efflux Pump Genes Mediating Ciprofloxacin Resistance in Staphylococcus Aureus Isolates in Sohag University Hospitals), which is not on this map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Detection of Efflux Pump Genes Mediating Ciprofloxacin Resistance in Staphylococcus Aureus Isolates in Sohag University Hospitals
Who cites it
13 citing papers in PubMed, 47 citations in OpenAlex.
- Panton-Valentine Leukocidin (PVL) genes may not be a reliable marker for community-acquired MRSA in the Dakahlia Governorate, Egypt.BMC microbiology · 2023Article
- Detection ofArchives of Razi Institute · 2021Article
- Molecular Characteristics of Methicillin-ResistantIranian journal of pathology · 2019Article
- Methicillin-ResistantThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2019Article
- Prevalence of Panton-Valentine Leukocidin Gene among Community AcquiredJournal of pathogens · 2018Article
- Distribution ofJournal of clinical and diagnostic research : JCDR · 2017Article
- Molecular Epidemiology Survey ofAdvanced biomedical research · 2017Article
- Molecular characterization of Staphylococcus aureus isolates causing skin and soft tissue infections in patients from Malakand, Pakistan.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016Article
- Association of Panton Valentine Leukocidin (PVL) genes with methicillin resistant Staphylococcus aureus (MRSA) in Western Nepal: a matter of concern for community infections (a hospital based prospective study).BMC infectious diseases · 2016Article
- Characterization of Staphylococcus aureus Biofilm Formation in Urinary Tract Infection.Iranian journal of public health · 2016Article
- Staphylococcus aureus Isolates Carrying Panton-Valentine Leucocidin Genes: Their Frequency, Antimicrobial Patterns, and Association With Infectious Disease in Shahrekord City, Southwest Iran.Jundishapur journal of microbiology · 2016Article
- The Prevalence ofAutoimmune diseases · 2016Article
- Action of cholecalciferol and alpha-tocopherol on Staphylococcus aureus efflux pumps.EXCLI journal · 2016Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStaphylococcus aureus has been recognized as a major human pathogen and is the major cause of nosocomial infections. Gamma-toxin, leukocidin and other bi-component toxins are a family of proteins encoded by the hlg and luk-PV, respectively. Panton-Valentine leukocidin (PVL) is an example of these toxins and causes leukocyte destruction and tissue necrosis. The aim of this study was to determine the prevalence of bi-component leukocidin in Methicillin Resistant Staphylococcus aureus (MRSA) isolates in staphylococcal infections.
methodsCollectively, 143 isolates of S. aureus were obtained from Tehran University of Medical Sciences hospitals and confirmed with biochemical tests. Then polymerase chain reaction was used to detect luk-PV loci and luk-E/D. Coagulase gene was used as internal control. The antibiotic susceptibility patterns of isolates were determined using disk diffusion method.
resultsOut of 149 S. aureus isolates 24.2% were luk-PV positive and 73.8% were luk-E/D positive.
conclusionThere was PVL positive MRSA isolates with high prevalence in evaluated hospitals. The diseases from these bacteria are with extensive necrosis, leucopenia and even death. We desire that, prevent from progress and death by diagnosis and right treatment.
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23112984PMC3468970W2117022080What OpenQuestion holds
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