ArticleKorean journal of orthodontics2012
Response of masticatory muscles to passive stretch stimulus - from perspectives of functional appliances.
Article in Korean journal of orthodontics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
objectiveThe aims of this study were to examine whether a passive stretch stimulus by means of a functional appliance induces changes in the fiber composition of masticatory muscles and whether these changes are similar to the changes in stretched limb muscle fibers by using RT-PCR, western blot, and immunohistochemical assays.
methodsFive male New Zealand White rabbits were fitted with a prefabricated inclined plane on the maxillary central incisors to force the mandible forward (- 2 mm) and downward (- 4 mm). Further, 1 hind limb was extended and constrained with a cast so that the extensor digitorum longus (EDL) was stretched when the animal used the limb. The animals were sacrificed after 1 week and the masseter, lateral pterygoid, and EDL were processed and compared with those from control animals (n = 3).
resultsThe stretched EDL had a significantly higher percentage of slow fibers, whereas the stretched masticatory muscles did not show changes in the composition of the major contractile proteins after 7 days.
conclusionsThe transition of fiber phenotypes in response to a stretch stimulus may take longer in the masticatory muscles than in the limb muscles.
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