ArticlePloS one2012
Transcriptome analysis of the Asian honey bee Apis cerana cerana.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Study on the molecular mechanism of colony strength of Apis cerana cerana based on transcriptomics.BMC genomics · 2026Article
- Body Size and Body Weight inLife (Basel, Switzerland) · 2026Article
- A Symbol of Immortality: Evidence of Honey in Bronze Jars Found in a Paestum Shrine Dating to 530-510 BCE.Journal of the American Chemical Society · 2025Article
- Article
- Full-Length Transcriptome Profile ofInternational journal of molecular sciences · 2024Article
- Prevalence of bee viruses in Apis cerana cerana populations from different locations in the Fujian Province of China.MicrobiologyOpen · 2019Article
- Dynamic transcriptome landscape of Asian domestic honeybee (Apis cerana) embryonic development revealed by high-quality RNA sequencing.BMC developmental biology · 2018Article
- Expression Characterization and Localization of the foraging Gene in the Chinese Bee, Apis cerana cerana (Hymenoptera: Apidae).Journal of insect science (Online) · 2018Article
- Proteomics Reveals the Molecular Underpinnings of Stronger Learning and Memory in Eastern Compared to Western Bees.Molecular & cellular proteomics : MCP · 2018Article
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- Reproductive switching analysis of Daphnia similoides between sexual female and parthenogenetic female by transcriptome comparison.Scientific reports · 2016Article
- Transcriptome Profile of the Asian Giant Hornet (Vespa mandarinia) Using Illumina HiSeq 4000 Sequencing: De Novo Assembly, Functional Annotation, and Discovery of SSR Markers.International journal of genomics · 2016Article
- The HEX 110 Hexamerin Is a Cytoplasmic and Nucleolar Protein in the Ovaries of Apis mellifera.PloS one · 2016Article
- Uncovering the novel characteristics of Asian honey bee, Apis cerana, by whole genome sequencing.BMC genomics · 2015Article
- Cross-modal interaction between visual and olfactory learning in Apis cerana.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2014Article
- Article
- Population genomics of the honey bee reveals strong signatures of positive selection on worker traits.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Gene expression profiling in winged and wingless cotton aphids, Aphis gossypii (Hemiptera: Aphididae).International journal of biological sciences · 2014Article
- A SNP based high-density linkage map of Apis cerana reveals a high recombination rate similar to Apis mellifera.PloS one · 2013Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Eastern hive honey bee, Apis cerana cerana is a native and widely bred honey bee species in China. Molecular biology research about this honey bee species is scarce, and genomic information for A. c. cerana is not currently available. Transcriptome and expression profiling data for this species are therefore important resources needed to better understand the biological mechanisms of A. c. cerana. In this study, we obtained the transcriptome information of A. c. cerana by RNA-sequencing and compared gene expression differences between queens and workers of A. c. cerana by digital gene expression (DGE) analysis.
resultsUsing high-throughput Illumina RNA sequencing we obtained 51,581,510 clean reads corresponding to 4.64 Gb total nucleotides from a single run. These reads were assembled into 46,999 unigenes with a mean length of 676 bp. Based on a sequence similarity search against the five public databases (NR, Swissport, GO, COG, KEGG) with a cut-off E-value of 10(-5) using BLASTX, a total of 24,630 unigenes were annotated with gene descriptions, gene ontology terms, or metabolic pathways. Using these transcriptome data as references we analyzed the gene expression differences between the queens and workers of A. c. cerana using a tag-based digital gene expression method. We obtained 5.96 and 5.66 million clean tags from the queen and worker samples, respectively. A total of 414 genes were differentially expressed between them, with 189 up-regulated and 225 down-regulated in queens.
conclusionsOur transcriptome data provide a comprehensive sequence resource for future A. c. cerana study, establishing an important public information platform for functional genomic studies in A. c. cerana. Furthermore, the DGE data provide comprehensive gene expression information for the queens and workers, which will facilitate our understanding of the molecular mechanisms of the different physiological aspects of the two castes.
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