ArticlePloS one2012
Groundwater contaminated with hexavalent chromium [Cr (VI)]: a health survey and clinical examination of community inhabitants (Kanpur, India).
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Human Health Effects of Oral Exposure to Chromium: A Systematic Review of the Epidemiological Evidence.International journal of environmental research and public health · 2024Pooled it
- Characterization and Application of Pr-Co Codoped BiFeOACS omega · 2026Article
- Hexavalent Chromium Induces Apoptosis and Autophagy in Human Neurons and Astrocytes via MAPK Pathway Activation.Biological trace element research · 2026Article
- Metabolic Mechanisms of Hexavalent Chromium-Induced Splenic Immune Injury via Oxidative Stress and Ferroptosis Pathways in New Zealand Rabbits.Metabolites · 2026Article
- Assessing Quality and Safety: Mineral and Metal Content in Local and Imported Honey From Dhaka City.Environmental health insights · 2026Article
- Cadmium and Chromium exposure associated with DNA hypermethylation of p16 tumor suppressor gene: a case-control study from endemic region of northern India.Clinical epigenetics · 2025Article
- Biosorption of Hexavalent Chromium byIndian journal of microbiology · 2025Article
- Electronic Textiles Based on Conductive Metal-Organic Frameworks as Scavengers and Sensors of Toxic Oxyanions from Water.Journal of the American Chemical Society · 2025Article
- Protective effects of the exogenous application of salicylic acid and chitosan on chromium-induced photosynthetic capacity and osmotic adjustment in Aconitum napellus.BMC plant biology · 2024Article
- Electrochemical Sensors for Heavy Metal Ion Detection in Aqueous Medium: A Systematic Review.ACS omega · 2024Review
- Equilibrium and kinetic modeling of Cr(VI) removal by novel tolerant bacteria species along with zero-valent iron nanoparticles.Scientific reports · 2024Article
- Reduced and oxidized rice straw biochar for hexavalent chromium adsorption: Revisiting the mechanism of adsorption.Heliyon · 2023Article
- Assessment of selected heavy metals in honey samples using flame atomic absorption spectroscopy (FAAS), Ethiopia.BMC chemistry · 2022Article
- Source apportionment and health risk assessment for potentially toxic elements in size-fractionated road dust in Busan Metropolitan City, Korea.Environmental monitoring and assessment · 2022Article
- Inhibition of Sirtuin-1 hyperacetylates p53 and abrogates Sirtuin-1-p53 interaction in Cr(VI)-induced apoptosis in the ovary.Reproductive toxicology (Elmsford, N.Y.) · 2022Article
- Drinking Water Quality and Public Health in the Kathmandu Valley, Nepal: Coliform Bacteria, Chemical Contaminants, and Health Status of Consumers.Journal of environmental and public health · 2022Article
- The reduction of Cr(VI) in Salvinia minima, possible involvement of an h-type thioredoxin.Environmental science and pollution research international · 2022Article
- Quality and human health risk assessment of uranium and other heavy metals in drinking water from Kwale County, Kenya.Environmental monitoring and assessment · 2021Article
- Heavy Metals and Human Health: Possible Exposure Pathways and the Competition for Protein Binding Sites.Molecules (Basel, Switzerland) · 2021Review
- Toxic Mechanisms of Five Heavy Metals: Mercury, Lead, Chromium, Cadmium, and Arsenic.Frontiers in pharmacology · 2021Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe assessed the health effects of hexavalent chromium groundwater contamination (from tanneries and chrome sulfate manufacturing) in Kanpur, India.
methodsThe health status of residents living in areas with high Cr (VI) groundwater contamination (N = 186) were compared to residents with similar social and demographic features living in communities having no elevated Cr (VI) levels (N = 230). Subjects were recruited at health camps in both the areas. Health status was evaluated with health questionnaires, spirometry and blood hematology measures. Cr (VI) was measured in groundwater samples by diphenylcarbazide reagent method.
resultsResidents from communities with known Cr (VI) contamination had more self-reports of digestive and dermatological disorders and hematological abnormalities. GI distress was reported in 39.2% vs. 17.2% males (AOR = 3.1) and 39.3% vs. 21% females (AOR = 2.44); skin abnormalities in 24.5% vs. 9.2% males (AOR = 3.48) and 25% vs. 4.9% females (AOR = 6.57). Residents from affected communities had greater RBCs (among 30.7% males and 46.1% females), lower MCVs (among 62.8% males) and less platelets (among 68% males and 72% females) than matched controls. There were no differences in leucocytes count and spirometry parameters.
conclusionsLiving in communities with Cr (VI) groundwater is associated with gastrointestinal and dermatological complaints and abnormal hematological function. Limitations of this study include small sample size and the lack of long term follow-up.
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