Evidence map›Paper›PMID 23112561›Full record

ArticleWorld journal of gastroenterology2012

Gastrointestinal stromal tumor presenting with prominent calcification.

Naoki Izawa, Takeshi Sawada, Ryuichi Abiko, Daisuke Kumon, Mami Hirakawa, Mika Kobayashi, Nobuyuki Obinata, Masahito Nomoto, Tadateru Maehata, Shun-ichi Yamauchi and 9 more

Open access · hybridAbstract readCase Reports
In one paragraph

Article in World journal of gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Calcified Small Bowel Mass.ACG case reports journal · 2021
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  9. Malignant abdominal rocks: where do they come from?Cancer imaging : the official publication of the International Cancer Imaging Society · 2013
    Review
  10. Unexpectedly ease surgery for a worrisome abdominal mass: Pedunculated GISTs.International journal of surgery case reports · 2013
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 1 institution in 1 country.

Naoki IzawaDivision of Gastroenterology and Hepatology, St. Marianna University School of Medicine, Kawasaki, Japan.
Takeshi Sawada
Ryuichi Abiko
Daisuke Kumon
Mami Hirakawa
Mika Kobayashi
Nobuyuki Obinata
Masahito Nomoto
Tadateru Maehata
Shun-ichi Yamauchi
Takefumi Kouro
Takashi Tsuda
Satoshi Kitajima
Hiroshi Yasuda
Keiichi Tanaka
Ichiro Tanaka
Masahiro Hoshikawa
Masayuki Takagi
Fumio Itoh
St. Marianna University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a rare case of a gastrointestinal stromal tumor (GIST) in the stomach with prominent calcification at presentation. A 61-year-old woman visited our hospital because of epigastric discomfort. A spherical calcified lesion with a diameter of about 30 mm was incidentally shown in the left upper quadrant on an abdominal X-ray. Computed tomography demonstrated that the tumor was growing from the upper gastric body, with calcification in the peripheral ring area. A laparoscopic partial gastrectomy was performed, and the resected specimen revealed a well-circumscribed tumor with exophytic growth from the gastric muscularis propria. Microscopic examination revealed spindle-shaped tumor cells with calcification and hemorrhage. Additionally, positive immunoreactivity of the tumor to KIT and CD34 and a low mitotic index resulted in the diagnosis of very low risk GIST. There are a few case reports of heavily calcified GIST, although solitary or punctate calcification of primary GIST has been reported in several case series. Dystrophic calcification of necrotic or degenerative tissue is the supposed cause of primary calcified GISTs. In contrast, appearance of calcification after administration of imatinib mesylate, which may be one indicator of disease response, is possibly caused by a different mechanism.

Indexed as

CalcinosisFemaleGastrointestinal NeoplasmsGastrointestinal Stromal TumorsHumansMiddle AgedCalcificationComputed tomographyGastrointestinal stromal tumorImatinib mesylateStomach

Identifiers

PMID23112561
PMCPMC3482655
OpenAlexW1607949515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.